Recent submissions

Clinical validation of liquid biopsy-RECIST (LB-RECIST) in metastatic colorectal cancer (mCRC) patients: findings from the PLATFORM-B study

MARTELLI, VALENTINO; vidal barrull, joana; Gibert Fernandez, Joan; Fernandez-Rodriguez, Concepción; Linares, Jenniffer; Elez, Elena; García-Alfonso, Pilar; Toledo, Rodrigo; Tabernero, Josep (Publication date: 2025-11-05)

Liquid biopsy; Metastatic colorectal cancer; Response assessment

Epigenetic synthetic lethality as a cancer therapeutic strategy: synergy of experimental and computational approaches

Fariña Morillas, Maria; Ollé i Monràs, Laia; de Rojas de Pablo, Isabel; Seoane Fernández, Jose Antonio; Maas, Silvana; Segura, Miguel F. (Publication date: 2025-11-03)

Synthetic lethality; Chromatin remodeling; Epidrugs

Randomised trial of trastuzumab deruxtecan and biology-driven selection of neoadjuvant treatment for HER2-positive breast cancer: a study protocol of ARIADNE

Naume, Bjørn; wildiers, hans; Sonke, Gabe; Karakatsanis, Andreas; Matikas, Alexios; DIECI, MARIA VITTORIA; Villacampa Javierre, Guillermo (Publication date: 2025-10-30)

Breast tumours; Drug therapy

Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer

Yu, Hui; Magoulopoulou, Anastasia; Amini, Rose-Marie; Chatzinikolaou, Maria Paraskevi; Horie, Masafumi; Lindberg, Amanda; Mezheyeuski, Artur (Publication date: 2025-10-30)

Clonality; Immune Checkpoint Inhibitor; Lung Cancer

Metabolic dysfunction-associated steatohepatitis reduces hepatic H2S-producing enzymes altering persulfidome composition

SHEN, TZU-KENG; Vignane, Thibaut; Gilglioni, Eduardo Hideo; Traini, Leonardo; Kalaitsidou, Elisavet; Conan, Pierre; Herranz Alzueta, Jose Mari (Publication date: 2025-10-30)

Steatohepatitis; Metabolic dysfunction; Persulfidome

Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer

Karta, Jessica; Meyers, Marianne; Rodriguez, Fabien; Koncina, Eric; Gilson, Cédric; Klein, Eliane; Alonso Landeira, Lidia; Aguilera Pujabet, Mònica; Nuciforo, Paolo (Publication date: 2025-10-30)

Fusobacterium nucleatum; Cancer-associated fibroblasts; Colorectal Cancer

Clinical Validity of FoundationOne Liquid CDx for Detection of BRAFV600E in Colorectal Cancer

Martini, Jean-Francois; Pasquina, Lincoln; Tunquist, Brian; Zhang, Xiaosong; Khaiser, Fatima; Yaeger, Rona; Tabernero, Josep (Publication date: 2025-10-29)

BRAF inhibitor; Colorectal cancer

White paper on best practices for translational research in neuroendocrine neoplasms

Cros, Jerome; Casanovas, Oriol; Castaño, Justo P.; Dayton, Talya; GIBERT, Benjamin; Garcia-Alvarez, Alejandro (Publication date: 2025-10-29)

Carcinoids; Genomics; Liquid biopsy

Optimization and validation of the international metabolic prognostic index for CD19 CAR-T in large B-cell lymphoma

Winkelmann, Michael; Raj, Sandeep S.; Müller, Fabian; Hansmann, Leo; Jain, Michael; IACOBONI, GLORIA; Barba, Pere (Publication date: 2025-10-29)

Metabolic prognostic index; CD19 CAR-T; Large B-cell lymphoma

Economic and Humanistic Burden of Triple-Negative Breast Cancer: A Systematic Literature Review

Huang, Min; Haiderali, Amin; Fox, Grace E.; Frederickson, Andrew; Cortés Castan, Javier; O’Shaughnessy, Joyce; Fasching, Peter A. (Publication date: 2022-09-09)

Triple-Negative Breast Cancer; Economic burden

Managing adverse events in patients with metastatic colorectal cancer receiving trifluridine/tipiracil in combination with bevacizumab

Elez, Elena; Calleja, Elizabeth; Caussé-Amellal, Nadia; Fakih, Marwan; Ciardiello, Fortunato; Prager, Gerhard (Publication date: 2025-08-12)

Adverse event; Metastatic colorectal cancer; Safety

Characterization and Clinical Implications of p53 Dysfunction in Patients With Myelodysplastic Syndromes

Zampini, Matteo; Riva, Elena; Lanino, Luca; SAUTA, ELISABETTA; Antunes dos Reis, Rita; Andrés Ejarque, Rosa María; Acha, Pamela (Publication date: 2025-09-05)

p53 dysfunction; Myelodysplastic syndromes

Presence of Ceramidase Activity in Electronegative LDL

Puig Calvó, Núria; Rives, Jose; Estruch Alrich, Montserrat; Aguilera-Simón, Ana; Rotllan, Noemi; Camacho, Mercedes; Colome Calls, Núria; Canals Suris, Francesc (Publication date: 2023-02-27)

Ceramide; Sphingomyelinase

Feasibility of Data-Driven, Model-Free Quantitative MRI Protocol Design: Application to Brain and Prostate Diffusion-Relaxation Imaging

Blumberg, Stefano B.; Battiston, Marco; Kakkar, Lebina S.; Lin, Hongxiang; Grussu, Francesco; Ianus, Andrada (Publication date: 2022-06-16)

Brain; Protocol design; Quantitative MRI (qMRI)

Primary tumour location, molecular alterations, treatments, and outcome in a population-based metastatic colorectal cancer cohort

Osterlund, Emerik; Sjöblom, Tobias; Hammarström, Klara; Nunes, Luis; Mathot, Lucy; Mezheyeuski, Artur (Publication date: 2025-08-12)

Primary tumour; Molecular alterations; Metastatic colorectal cancer

Hitting the brakes on autophagy for overcoming acquired resistance in triple negative breast cancer

Villanueva Cardús, Josep; Bellio, Chiara (Publication date: 2021-11-10)

Càncer de mama triple negatiu; Autofàgia; Resistència terapèutica

The impact of COVID-19 on cancer care and oncology clinical research: an experts’ perspective

Sessa, C.; Cortés Castan, Javier; Conte, P.; Cardoso, Fatima; Choueiri, T.; Dummer, R.; Tabernero Caturla, Josep (Publication date: 2022-07-22)

COVID-19; Cancer care; Clinical research

INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors

Li, Qing; Jiang, Baishan; Guo, Jiaye; Shao, Hong; Del Priore, Isabella; Chang, Qing; Palafox Sánchez, Marta; Serra Elizalde, Violeta (Publication date: 2023-04-20)

Proteïnes supressores de tumors; Inhibidors de la quinasa

The INSIGHT study: a randomized, Phase III study of ripretinib versus sunitinib for advanced gastrointestinal stromal tumor with KIT exon 11 + 17/18 mutations

Chi, Ping; Somaiah, Neeta; George, Suzanne; Blay, Jean-Yves; Jones, Robin; Serrano, Cesar (Publication date: 2024-10-25)

KIT mutations; Gastrointestinal stromal tumor; Targeted therapy

Unlocking the potential of engineered immune cell therapy for solid tumors

Albarran Fernandez, Victor; Urbano-Ispizua, Alvaro; Guedan Carrio, Sonia; Angelats, Laura; Delgado, Julio; Gros, Alena (Publication date: 2025-04-01)

Immune cell therapy; Solid tumors

Articles científics - VHIO: Recent submissions

Clinical validation of liquid biopsy-RECIST (LB-RECIST) in metastatic colorectal cancer (mCRC) patients: findings from the PLATFORM-B study ﻿

Epigenetic synthetic lethality as a cancer therapeutic strategy: synergy of experimental and computational approaches ﻿

Randomised trial of trastuzumab deruxtecan and biology-driven selection of neoadjuvant treatment for HER2-positive breast cancer: a study protocol of ARIADNE ﻿

Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer ﻿

Metabolic dysfunction-associated steatohepatitis reduces hepatic H2S-producing enzymes altering persulfidome composition ﻿

Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer ﻿

Clinical Validity of FoundationOne Liquid CDx for Detection of BRAFV600E in Colorectal Cancer ﻿

White paper on best practices for translational research in neuroendocrine neoplasms ﻿

Optimization and validation of the international metabolic prognostic index for CD19 CAR-T in large B-cell lymphoma ﻿

Economic and Humanistic Burden of Triple-Negative Breast Cancer: A Systematic Literature Review ﻿

Managing adverse events in patients with metastatic colorectal cancer receiving trifluridine/tipiracil in combination with bevacizumab ﻿

Characterization and Clinical Implications of p53 Dysfunction in Patients With Myelodysplastic Syndromes ﻿

Presence of Ceramidase Activity in Electronegative LDL ﻿

Feasibility of Data-Driven, Model-Free Quantitative MRI Protocol Design: Application to Brain and Prostate Diffusion-Relaxation Imaging ﻿

Primary tumour location, molecular alterations, treatments, and outcome in a population-based metastatic colorectal cancer cohort ﻿

Hitting the brakes on autophagy for overcoming acquired resistance in triple negative breast cancer ﻿

The impact of COVID-19 on cancer care and oncology clinical research: an experts’ perspective ﻿

INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors ﻿

The INSIGHT study: a randomized, Phase III study of ripretinib versus sunitinib for advanced gastrointestinal stromal tumor with KIT exon 11 + 17/18 mutations ﻿

Unlocking the potential of engineered immune cell therapy for solid tumors ﻿