Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Author

Bardina i Simorra, Xavier

Fernández, Laura

Piñeiro, Elisabet

Surrallés i Calonge, Jordi

Velázquez Henar, Antonia

Publication date

2006

Abstract

The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

Document Type

Article

Language

English

Subjects and keywords

Inverse regression problem; Subtoxic concentration; Confidence interval

Publisher

 

Related items

SORT : statistics and operations research transactions ; Vol. 30, Núm. 2 (July-December 2006), p. 193-204

Rights

open access

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