Recerca: articles, congressos, llibres: Recent submissions
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"Paper White" characters and the desire for homogeneity in spanish-language picturebooks
In this article, we examine a corpus of recommended Spanish-language picturebooks published in Spain and Latin America between 2012-2018. We examine a corpus of fifty-six books that have received awards or are highlighted ...
CRISPR-engineered human GATA2 deficiency model uncovers mitotic dysfunction and premature aging in HSPCs, impairing hematopoietic fitness
GATA2 deficiency is a monogenic transcriptopathy disorder characterized by bone marrow failure (BMF), immunodeficiency, and a high risk of developing myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). Although ...
Do the health benefits of the Mediterranean diet increase with a higher proportion of whole plant-based foods?
Purpose of Review: This review aims to explore the potential health effects of increasing the proportion of whole plant-based foods within a Mediterranean diet (MedDiet), summarize the available evidence, and provide ...
Redefining omalizumab discontinuation in chronic spontaneous urticaria: the value of optimization and predictive factors of relapse. A 52-week multicenter study
Background: Patients with chronic spontaneous urticaria frequently relapse after discontinuing omalizumab and require its reintroduction. Although prior optimization might reduce recurrences, there is scarce evidence on ...
Genetic polymorphisms in psoriasis: investigating genetic variations for precise profiling of response to brodalumab in real-life clinical practice
Background: Numerous studies have investigated the association that exists between genetic variants and the efficacy profile of biologic therapies for the management of psoriasis. However, as far as we know, data on this ...
Is a single lethal electric field threshold sufficient to characterize the lesion size in computational modeling of cardiac pulsed-field ablation?
Background: Pulsed-field ablation (PFA) is a novel cardiac ablation technology based on irreversible electroporation (IRE). PFA computational models rely on identification of a lethal electric field threshold to predict ...
Brain [18F]FDG uptake patterns in type 2 diabetes: new phenotypes relating to biomarkers of cognitive impairment
Previous studies in patients without Type 2 diabetes suggest that brain hypo- and hypermetabolic regions may indicate risk for cognitive disorders. We aimed to study these brain glucose uptake patterns in Type 2 diabetes ...
Meta-UNet: enhancing skin-lesion segmentation with multimodal feature integration and uncertainty estimation
Purpose. Medical image segmentation plays a crucial role in diagnostic pipelines. This study investigates the integration of lesion-specific metadata with image data to enhance segmentation accuracy and reduce predictive ...
From genetics to psychosocial functioning: unraveling the mediating roles of cognitive reserve, cognition, and negative symptoms in first-episode psychosis
Background: Studies have shown associations between polygenic risk scores for educational attainment (PRSEA), cognitive reserve (CR), cognition, negative symptoms (NS), and psychosocial functioning in first-episode psychosis ...
Diabetic foot ulcers segmentation challenge report: benchmark and analysis
Monitoring the healing progress of diabetic foot ulcers is a challenging process. Accurate segmentation of foot ulcers can help podiatrists to quantitatively measure the size of wound regions to assist prediction of healing ...
Longitudinal assessment of abnormal cortical folding in fetuses and neonates with isolated non-severe ventriculomegaly
Purpose: The impact of ventriculomegaly (VM) on cortical development and brain functionality has been extensively explored in existing literature. VM has been associated with higher risks of attention-deficit and hyperactivity ...
Changes in local endocardial electrograms immediately after PFA show dose-dependent variations
Background/Introduction. Pulsed field ablation (PFA) is a novel nonthermal cardiac ablation technology based on irreversible electroporation. The behaviour of local electrograms after PFA has been poorly characterized and ...
Stabilizing the shield: C-Terminal tail mutation of HMPV F protein for enhanced vaccine design
Background: Human Metapneumovirus (HMPV) is a respiratory virus in the Pneumoviridae family. HMPV is an enveloped, negative-sense RNA virus encoding three surface proteins: SH, G, and F. The highly immunogenic fusion (F) ...
Unveiling learning trends in convolutional neural networks with dynamic mode decomposition
The widespread adoption of pre-trained models in artificial intelligence poses several evaluation challenges, primarily due to limited access to comprehensive information including training data, test data, loss function, ...
Uncertainty-aware segmentation quality prediction via deep learning Bayesian modeling: comprehensive evaluation and interpretation on skin cancer and liver segmentation
Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual ...
Initial evaluation of a new cervical screening strategy combining human papillomavirus genotyping and automated visual evaluation: the Human Papillomavirus-Automated Visual Evaluation Consortium
The HPV-Automated Visual Evaluation Consortium is validating a cervical screening strategy enabling accurate cervical screening in resource-limited settings. A rapid, low-cost human papillomavirus (HPV) assay permits ...
The multiomics blueprint of the individual with the most extreme lifespan
Extreme human lifespan, exemplified by supercentenarians, presents a paradox in understanding aging: despite advanced age, they maintain relatively good health. To investigate this duality, we have performed a high-throughput ...
Development and comparison of reference equations for the six-minute walk test in spanish healthy adults aged 45-85 years
Objectives: (i) To develop sex-specific reference equations to predict distance walked (6MWD) in the 6-minute walk test (6MWT), in healthy subjects aged 45-85 years, from different geographic areas of Spain; and (ii) to ...
Spatial Bayesian distributed lag non-linear models with R-INLA
M.Q.-Z. and J.B. gratefully acknowledge funding from the European Union's Horizon 2020 and Horizon Europe research and innovation programmes under grant agreement nos 865564 (European Research Council Consolidator ...
