Articles publicats Departament de Ciències Mèdiques

Universitat de Girona Facultat de Lletres

La Universitat de Girona és una institució pública que cerca l’excel·lència en la docència i en la recerca, i que participa en el progrés i el desenvolupament de la societat, mitjançant la creació, transmissió, difusió i crítica de la ciència, la tècnica, les humanitats, les ciències socials i les arts.La Universitat de Girona està arrelada al país i a la cultura catalana i és un dels principals motors econòmics i culturals del seu entorn. Al mateix temps, expressa la vocació d’universalitat i d’obertura a totes les tradicions, avenços i cultures.La Universitat té la seva seu a la ciutat de Girona i s’integra en el sistema d’universitats públiques catalanes.


Si sou autor/a d’algun document elaborat en l’àmbit de la Universitat de Girona i voleu publicar-lo a RECERCAT, contacteu amb recercat@udg.edu.

Recent Submissions

Inferences about fossil hominin locomotion through 3D morphometric analysis of wrist ligament insertion sites 

Casado, Aroa; Martínez-Liria, Xavier; San-Millán, Marta; Menés, Laura; Ciurana, Neus; García-Cuesta, Marcel; Rodríguez Cabeza, Patrícia; Pastor, Francisco; Cabo, Roberto; Potau Ginés, Josep Maria (2025-11-27)

Understanding the evolution of wrist anatomy in fossil hominins is essential for reconstructing their locomotor behavior and manipulative capabilities. Traditionally, most studies have focused on bone morphology, overlooking ...

Prevalence of directional asymmetry within the acetabulum and its implications for age estimation 

Warrier, Varsha; San-Millán, Marta; Kanchan, Tanuj (2025-12-06)

Age estimation is a prerequisite for human identification. Within the skeletal framework, pelvic acetabular variables constitute a promising age marker. Previous investigations with the coxal bone have utilised either ...

REIV-TOXO Project: Results from a Spanish cohort of congenital toxoplasmosis (2015-2022). The beneficial effects of prenatal treatment on clinical outcomes of infected newborns 

Guarch-Ibáñez, Borja; Carreras-Abad, Clara; Frick, Marie Antoinette; Blazquez-Gamero, Daniel; Baquero-Artigao, Fernando; Fuentes, Isabel; Soler Palacín, Pere; Spanish Research Network of Congenital Toxoplasmos (2024-10-22)

Background: Some regions of Spain are withdrawing their pregnancy screening program for congenital toxoplasmosis (CT). The Spanish Research Network of Congenital Toxoplasmosis (REIV-TOXO) was created to describe the current ...

Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation 

Latorre Luque, Jèssica; Díaz-Trelles, Ramon; Comas Vila, Ferran; Gavaldà i Navarro, Aleix; Milbank, Edward; Dragano, Nathalia; Morón-Ros, Samantha; Mukthavaram, Rajesh; Ortega, Francisco; Castells Nobau, Anna; Oliveras-Cañellas, Núria; Ricart, Wifredo; Karmali, Priya P.; Tachikawa, Kiyoshi; Chivukula, Pad; Villarroya i Gombau, Francesc; López, Miguel; Giralt i Oms, Marta; Fernández-Real Lemos, José Manuel; Moreno Navarrete, José María (2022-09-13)

Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically ...

Cardiovascular Risk Age Reflects Arterial Status: Middle-Aged People Showed Equivalent Arterial Stiffness to Older People in the Same Risk Category 

Alves Cabratosa, Lia; Elosua Bayés, Marc; Martí Lluch, Ruth; Blanch, Jordi; Tornabell Noguera, Eric; García Gil, María del Mar; Ponjoan Thäns, Anna; Grau, María; Ribas Aulinas, Francesc; Zacarías-Pons, Lluís; Marrugat, Jaume; Ramos Blanes, Rafel (2024)

The concept of risk age may help overcome an excessive weight of age in cardiovascular risk functions. This study aimed to evaluate the equivalence of risk age with arterial stiffness by comparing people with increased ...

Long COVID: cognitive, balance, and retina manifestations 

Carmona Cervelló, Meritxell; León-Gómez, Brenda Biaani; Dacosta-Aguayo, Rosalia; Lamonja-Vicente, Noemí; Montero-Alía, Pilar; Molist, Gemma; Ayet, Aitana; Chacón, Carla; Costa-Garrido, Anna; López-Lifante, Victor M.; Zamora-Putin, Valeria; Liutsko, Liudmila; García-Sierra, Rosa; Fornés, Antònia; Moreno-Gabriel, Eduardo; Massanella, Marta; Muñoz-Moreno, Jose A.; Rodríguez-Pérez, M. Carmen; Mateu, Lourdes; Prats, Anna; Mataró, Maria; Boigues, Marc; Quirant, Bibiana; Prado, Julia G.; Martínez-Cáceres, Eva; Violán Fors, Concepción; Toran Monserrat, Pere; APC Collaborative Group (2024-07-05)

Background: The neurological symptoms of Long COVID (LC) and the impact of neuropsychological manifestations on people’s daily lives have been extensively described. Although a large body of literature describes symptoms, ...

An expert patient program to improve the empowerment and quality of life of people with multiple sclerosis: protocol for a multicenter pre-post intervention study 

Robles Sánchez, Miguel Ángel; Amil-Bujan, Paloma; Bosch Farré, Cristina; Coll-Martinez, Clàudia; Arévalo Navinés, María Jesús; Anglada, Elisenda; Menéndez, Rebeca; Montalban Gairín, Xavier; Sastre Garriga, Jaume; Ramió i Torrentà, Lluís; Bertran i Noguer, Carme (2023-05-18)

Introduction: Multiple sclerosis (MS) causes a progressive disability, which substantially impacts the quality of life (QoL). Health interventions that meet the needs and demands of people with MS are essential to minimize ...

Association of depression phenotypes and antidepressant treatment with mortality due to cancer and other causes: a community-based cohort study 

Vilalta Lacarra, Anna; Vilalta Franch, Joan; Serrano Sarbosa, Domènec; Martí Lluch, Ruth; Marrugat, Jaume; Garre Olmo, Josep (2023-08-24)

Objective: This study aimed to assess the association of somatic depressive symptoms (SDS), cognitive/emotional depressive symptoms (C-EDS), and antidepressant treatment on mortality due to cancer and other causes in a ...

Combined Systemic and cutaneous ovalbumin-aluminum sensitization triggers thermal hyperalgesia, spinal gliosis, and nociceptive nerve fibers sprouting in mice 

Siquier-Dameto, Gabriel; Gimeno-Beltrán, Javier; Bellia, Gilberto; Boadas i Vaello, Pere; Verdú Navarro, Enrique (2025-09-11)

Background/Objectives: This study investigates whether systemic ovalbumin-aluminum sensitization followed by cutaneous challenge induces thermal hyperalgesia and spinal cord gliosis in mice. Methods: Adult female ICR-CD1 ...

More Than Three Decades After Discovery of the Neuroprotective Effect of PACAP, What Is Still Preventing Its Clinical Use? 

Cherait, Asma; Xifró i Collsamata, Xavier; Reglodi, Dora; Vaudry, David (2025-06-21)

Discovered in 1989, pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide with strong neuroprotective properties, as shown in various neurodegenerative preclinical models of Parkinson, Alzheimer, or ...

Population-based analysis of breast cancer incidence and mortality: overall and age-specific temporal trends over 40-year period in Girona, Spain 

Sanvisens, Arantza; Vidal-Vila, Anna; Puigdemont, Montserrat; Viñas, Gemma; Roqué Lloveras, Ariadna; Barco, Sonia del; Perez Bueno, Ferran; Trallero, Jan; Marcos-Gragera, Rafael; Renart i Vicens, Gemma (2025-04-25)

Purpose: Breast cancer (BC) incidence and mortality in women have changed over time. This study aims to analyze population-level incidence and mortality trends over 40 years of observation. Methods: Population-based study ...

Repeated Administrations of Polyphenolic Extracts Prevent Chronic Reflexive and Non-Reflexive Neuropathic Pain Responses by Modulating Gliosis and CCL2-CCR2/CX3CL1-CX3CR1 Signaling in Spinal Cord-Injured Female Mice 

Bagó Mas, Anna; Korimová, Andrea; Bretová, Karolina; Deulofeu, Meritxell; Verdú Navarro, Enrique; Fiol Santaló, Núria; Dubový, Petr; Boadas i Vaello, Pere (2025-04-02)

Neuropathic pain after spinal cord injury lacks any effective treatments, often leading to chronic pain. This study tested whether the daily administration of fully characterized polyphenolic extracts from grape stalks and ...

Longitudinal Analysis of Placental IRS1 DNA Methylation and Childhood Obesity 

Gómez-Vilarrubla, Ariadna; Niubó-Pallàs, Maria; Mas Parés, Berta; Bonmatí Santané, Alexandra; Martínez-Calcerrada, José María; López Ibáñez, Beatriz; Peñas Cruz, Aaron; Zegher, Francis de; Ibáñez, Lourdes; López-Bermejo, Abel; Bassols Casadevall, Judit (2025-03-28)

Accumulating evidence suggests that the predisposition to metabolic diseases is established in utero through epigenomic modifications. However, it remains unclear whether childhood obesity results from preexisting epigenomic ...

Soluble receptors for advanced glycation endproducts are predictors of insulin sensitivity and affected by weight loss 

Moreno Navarrete, José María; Leal Moncada, Yenny Teresa; Rosell Díaz , Marisel; Fernández-Real Lemos, José Manuel (2024-10-19)

Background Mice experiments have underscored the efficacy of pharmacological inhibition of advanced glycation endproducts (AGEs) through the use of soluble receptors for advanced glycation endproducts (sRAGE) in mitigating ...

Health-Related Quality of Life in Men with Fractures and Fear of Falling in General Population: A Cross-Sectional Study 

Zwart Salmerón, Marta; Azagra Ledesma, Rafael; Díaz Herrera, Miguel Ángel; Pujol Salud, Jesús; Sáez Zafra, Marc; Aguyé Batista, Amada (2025-01-30)

Purpose: This study aims to assess how fractures and fear of falling affect health-related quality of life (HRQoL) in men (≥50 years) across different domains. Methods: Design: Observational study. Setting: Primary care. ...

Case Reports: full facial rejuvenation with definisse fillers 

Siquier-Dameto, Gabriel; Hernández Malgapo, Dennis Malvin (2023-05-19)

Background: Several known factors contribute to the visible signs of facial aging. Changes in dentition and bony architecture, facial fat loss, diminished dermal thickness, and loss of dermal and subcutaneous support ...

Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment 

Peracaula Domínguez, Míriam; Sebastián, Laura; Francisco Albesa, Iria; Bonnin Vilaplana, Marc; Rodriguez Chiaradía, Diego A.; Tura-Ceide, Olga (2024-08-23)

Pulmonary Embolism (PE) is a life-threatening condition initiated by the presence of blood clots in the pulmonary arteries, leading to severe morbidity and mortality. Underlying mechanisms involve endothelial dysfunction, ...

Subcutaneous Injection and brush application of ovalbumin-aluminum salt solution induces dermatitis-like changes in mice 

Siquier-Dameto, Gabriel; Iguaran-Pérez, Ainhoa; Gimeno-Beltrán, Javier; Bellia, Gilberto; Giori, Andrea Maria; Boadas i Vaello, Pere; Verdú Navarro, Enrique (2025-03-03)

Background: Intraperitoneal sensitization combined with topical and/or epicu- taneous treatment using an ovalbumin (OVA)-aluminum salt solution (OVA-AL) repre- sents a model for inducing atopic dermatitis (AD). However, ...

The solvent chosen for the manufacturing of electrospun polycaprolactone scaffolds influences cell behavior of lung cancer cells 

Polonio Alcalá, Emma; Casanova Batlle, Enric; Puig i Miquel, Teresa; Ciurana, Quim de (2022-11-14)

The development of a trustworthy in vitro lung cancer model is essential to better understand the illness, find novel biomarkers, and establish new treatments. Polycaprolactone (PCL) electrospun nanofibers are a cost-effective ...

Application of the adverse outcome pathway to identify molecular changes in prenatal brain programming induced by IUGR: Discoveries after EGCG exposure 

Kühne, Britta A.; Teixidó, Elisabet; Ettcheto, Miren; Puig i Miquel, Teresa; Planas i Grabuleda, Marta; Feliu Soley, Lidia; Pla, Laura; Campuzano, Victoria; Gratacós, Eduard; Fritsche, Ellen; Illa, Miriam; Barenys, Marta (2022-10-29)

Following a multi-disciplinary approach integrating information from several experimental models we have collected new evidence supporting, expanding and redesigning the AOP 'Disrupted laminin/int-β1 interaction leading ...

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