Centres Científics i Tecnològics de la Universitat de Barcelona (CCiTUB): Recent submissions
Now showing items 61-76 of 76
Purification of replicating pancreatic β-cells for gene expression studies
β-cell proliferation is a rare event in adult pancreatic islets. To study the replication-related β-cell biology we designed a replicating β-cells sorting system for gene expression experiments. Replicating β-cells were ...
Probing the Kinetic and Thermodynamic Fingerprints of Anti-EGF Nanobodies by Surface Plasmon Resonance
Despite the widespread use of antibodies in clinical applications, the precise molecular mechanisms underlying antibody-antigen (Ab-Ag) interactions are often poorly understood. In this study, we exploit the technical ...
No Switching Cooperativity between Coordinated Azo Ligands on Complexes Having $M^{II}(phosphane-k^2P)\}^{2+}\ ( M = Pd, Pt)$ Scaffolds
A series of square-planar palladium and platinum compounds with cis-blocking phosphanes and terminal azobenzene ligands ${[M(dppp)-(azo)_{2}] (OTf)_{2} (azo = CN(C_{6}H_{4})-N = N-(C_{6}H_{4})CN (iso-cyano), CN(C_{6}H_{4})-N ...
A comprehensive characterisation of beer polyphenols by high resolution mass spectrometry (LC-ESI-LTQ-Orbitrap-MS)
Beer is the second most consumed alcoholic beverage in Europe and shown by the European Prospective Investigation into Cancer and Nutrition cohort study to be the main food contributor to hydroxybenzoic acid intake. About ...
A Novel, Extremely Bioavailable Cocrystal of Pterostilbene
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold ...
Construction of Zn(II) Linear Trinuclear Secondary Building Units from A Coordination Polymer Based on α-Acetamidocinnamic Acid and 4-Phenylpyridine
The synthesis and characterization of one coordination polymer and two trinuclear complexes are presented. The coordination polymer [Zn2( -O,O'-ACA)2(ACA)2(4-Phpy)2]n (1) has been obtained by the reaction between Zn(OAc)2 ...
Proline cis-trans isomerization and its implications for the dimerization of analogues of cyclopeptide stylostatin 1: a combined computational and experimental study
Cis and trans proline conformers are often associated with dramatic changes in the biological function of peptides. A slow equilibrium between cis and trans Ile-Pro amide bond conformers occurs in constrained derivatives ...
Crystal engineering studies: polymorphs and co-crystals
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166
On the uptake of cationic liposomes by cells: from changes in elasticity to internalization
In this study, we assessed the capacity of a previously reported engineered liposomal formulation, which had been tested against model membranes mimicking the lipid composition of the HeLa plasma membrane, to fuse and ...
Nuclear magnetic resonance
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166
Deciphering the stack, a novel bacterial structure, by (cryo-) transmission electron microscopy and (cryo-) electron tomography
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/120717
The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice
p38 MAPK activity plays an important role in several steps of the osteoblast lineage progression through activation of osteoblast-specific transcription factors and it is also essential for the acquisition of the osteoblast ...
Secondary Ion Mass Spectrometry (SIMS): principles and applications
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166
Atomic force microscopy: probing the nanoworld
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166
Vestibular toxicity of cis-2-pentenenitrile in the rat
cis-2-Pentenenitrile, an intermediate in the synthesis of nylon and other products, causes permanent behavioral deficits in rodents. Other low molecular weight nitriles cause degeneration either of the vestibular sensory ...
In Situ visualization of the local photothermal effect produced on α-CycloNataly Silvadextrin inclusion compound associated with gold nanoparticles
Evidence of guest migration in α-cyclodextrin-octylamine (α-CD-OA) inclusion compound (IC) generated via plasmonic heating of gold nanoparticles (AuNPs) has been studied. In this report, we demonstrate local effects generated ...
