Mostrando ítems 1-20 de 632

    White matter diffusion estimates in obsessive-compulsive disorder across 1653 individuals: machine learning findings from the ENIGMA OCD Working Group.  

    Kim, Bo-Gyeom; Kim, Gakyung; Abe, Yoshinari; Alonso Ortega, María del Pino; Ameis, Stephanie H.; Anticevic, Alan; Arnold, Paul D.; Balachander, Srinivas; Banaj, Nerisa; Bargalló Alabart, Núria; Batistuzzo, Marcelo C.; Benedetti, Francesco; Bertolín Triquell, Sara; Beucke, Jan C.; Bollettini, Irene; Brem, Silvia; Brennan, Brian P.; Buitelaar, Jan K.; Calvo Escalona, Rosa; Castelo-Branco, Miguel; Cheng, Yuqi; Chhatkuli, Ritu Bhusal; Ciullo, Valentina; Coelho, Anna; Couto, Beatriz; Dallaspezia, Sara; Ely, Benjamin A.; Ferreira, Sónia; Fontaine, Martine; Fouche, Jean Paul; Grazioplene, Rachael G.; Gruner, Patricia; Hagen, Kristen; Hansen, Bjarne; Hanna, Gregory L.; Hirano, Yoshiyuki; Höxter, Marcelo Q.; Hough, Morgan; Hu, Hao; Huyser, Chaim; Ikuta, Toshikazu; Jahanshad, Neda; James, Anthony; Jaspers-Fayer, Fern; Kasprzak, Selina; Kathmann, Norbert; Kaufmann, Christian; Kim, Minah; Koch, Katharina; Kvale, Gerd; Kwon, Jun Soo; Lázaro García, Luisa; Lee, Junhee; Lochner, Christine; Lu, Jin; Rodriguez Manrique, Daniela; Martínez Zalacaín, Ignacio; Masuda, Yoshitada; Matsumoto, Koji; Maziero, Maria Paula; Menchón Magriñá, José Manuel; Minuzzi, Luciano; Moreira, Pedro Silva; Morgado, Pedro; Narayanaswamy, Janardhanan C.; Narumoto, Jin; Ortiz García, Ana Encarnación; Ota, Junko; Pariente, Jose Carlos; Perriello, Chris; Picó Pérez, Maria; Pittenger, Christopher; Poletti, Sara; Real, Eva; Reddy, Y. C. Janardhan; Rooij, Daan van; Sakai, Yuki; Sato, João R; Segalàs Cosi, Cinto; Shavitt, Roseli G.; Shen, Zonglin; Shimizu, Eiji; Shivakumar, Venkataram; Soriano Mas, Carles; Sousa, Nuno; Sousa, Mafalda Machado de; Spalletta, Gianfranco; Stern, Emily R.; Stewart, S. Evelyn; Szeszko, Philip R.; Thomas, Rajat; Thomopoulos, Sophia I.; Vecchio, Daniela; Venkatasubramanian, Ganesan; Vriend, Chris; Walitza, Susanne; Wang, Zhen; Watanabe, Anri; Wolters, Lidewij H.; Xu, Jian; Yamada, Kei; Yun, Je-Yeon; Zarei, Mojtaba; Zhao, Qin; Zhu, Xi; ENIGMA-OCD working group; Thompson, Paul M.; Bruin, Willem B.; Wingen, Guido van; Piras, Federica; Piras, Fabrizio; Stein, Dan J., 1962-; Heuvel, Odile A. van den; Simpson, Helen Blair; Marsh, Rachel; Cha, Jiook (Fecha de publicación: 2026-04-09)

    White matter pathways, typically studied with diffusion tensor imaging (DTI), have been implicated in the neurobiology of obsessive-compulsive disorder (OCD). However, due to limited sample sizes and the predominance of ...

    Emotional intelligence and neurocognition profiles in first-episode psychosis: A two-year follow-up study 

    Clougher, Derek; Forte, Maria Florencia; Mezquida Mateos, Gisela; Sánchez Torres, Ana M.; Serra Navarro, Maria; Penadés Rubio, Rafael; Lobo, Antonio; González-Pinto, Ana; Panadero Gómez, Rocío; Roldán, Alexandra; Vieta i Pascual, Eduard, 1963-; Serna, Elena de la, 1978-; Trabsa, Amira; Martínez-Arán, Anabel, 1971-; Torrent Font, Carla; Tortorella, Alfonso; Menculini, Giulia; Ramos-Quiroga, Josep Antoni; Cuesta, Manuel J.; Bernardo Arroyo, Miquel; Amoretti Guadall, Silvia; PEPs Group (Fecha de publicación: 2025-10-09)

    Emotional intelligence (EI) and neurocognition (NC) impairments are common in first-episode psychosis (FEP), yet their evolution over time remains unclear. This study identified patient profiles in EI and NC performance ...

    Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia 

    Gimenez, Neus; Tripathi, Rupal; Giró, Ariadna; Rosich, Laia; López Guerra, Mónica; López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; Mas, José Manuel; Pérez Galán, Patricia; Delgado, Julio (Delgado González); Campo Güerri, Elias; Farrés, Judith; Colomer Pujol, Dolors (Fecha de publicación: 2025-10-23)

    Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL ...

    Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets 

    López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; López Guerra, Mónica; Colomer Pujol, Dolors (Fecha de publicación: 2025-09-26)

    Chronic lymphocytic leukemia (CLL) is characterized by a high degree of genetic variability and interpatient heterogeneity. In the last decade, novel alterations have been described. Some of them impact on the prognosis ...

    SF3B1 mutation-mediated sensitization to H3B-8800 splicing inhibitor in chronic lymphocytic leukemia 

    López Oreja, Irene; Gohr, Andre; Playa-Albinyana, Heribert; Giró, Ariadna; Arenas Ríos, Fabián; Higashi, Morihiro; Tripathi, Rupal; López Guerra, Mónica; Irimia Martínez, Manuel; Aymerich Gregorio, Marta; Valcárcel Juárez, Juan; Bonnal, Sophie; Colomer Pujol, Dolors (Fecha de publicación: 2025-11-12)

    Splicing factor 3B subunit 1 (SF3B1) is involved in pre-mRNA branch site recognition and is the target of antitumor-splicing inhibitors. Mutations in SF3B1 are observed in 15% of patients with chronic lymphocytic leukemia ...

    Imaging Efficacy of [18F]CTT1057 PET/CT in Patients with Biochemically Recurrent Prostate Cancer: Results from GuidePath-A Phase 3, Prospective Multicenter Study 

    Fanti, Stefano; Robles Barba, Javier Jesus; Behr, Spencer; Maurer, Tobias; Paredes Barranco, Pilar; Walz, Jochen; Duch, Joan; Simo Perdigo, Marc; Mainta, Ismini Charis; Bonnefoy, Pierre Benoit; Coulanges, Medge; Tang, Jun; Seigne, Christelle; Wilke, Celine; Catafau, Ana M.; Iagaru, Andrei; Aggarwal, Rahul (Fecha de publicación: 2025-09-25)

    Improved diagnostic accuracy in patients with prostate cancer at first biochemical recurrence (BCR) with low prostate-specific antigen (PSA) levels is needed. This prospective study (GuidePath; NCT04838613) aimed to evaluate ...

    A low total metabolic tumor volume independently predicts for a longer time to first treatment in initially observed, low tumor burden follicular lymphoma 

    Mozas, Pablo; Casanueva Eliceiry, Sebastián; Rivero, Andrea; Serna, Ángel; Simó, Marc; Rodríguez, Sonia; Rivas Delgado, Alfredo; Nadeu, Ferran; Correa, Juan Gonzalo; Piñeyroa, Juan Antonio; Pérez-Valencia, Amanda Isabel; Guinetti-Ortiz, Katia; Gómez-Hernando, Marta; Giné, Eva; Delgado, Julio; Villamor i Casas, Neus; Campo, Elías; Magnano, Laura; Abrisqueta Costa, Pau; Setoain Perego, Xavier; López-Guillermo, Aramando (Fecha de publicación: 2025-01-23)

    Watchful waiting is an acceptable management strategy for advanced-stage, low tumor burden (LTB) patients with follicular lymphoma (FL). However, the prediction of how long this treatment-free observation period will last ...

    Diagnóstico prequirúrgico de gliomas difusos en adultos: perspectivas prácticas de radiólogos de Unidades de neurooncología Post-WHO 2021 

    Pons Escoda, Albert; Majós Torró, Carlos; Smits, Marion; Oleaga Zufiría, Laura (Fecha de publicación: 2024-08-30)

    La Clasificación 2021 de tumores del sistema nervioso central (SNC) por la Organización Mundial de la Salud (OMS) fue acogida con entusiasmo, aunque al principio pudo parecer abrumadora. Con el tiempo, hemos comprendido ...

    Dissemination of NDM-producing Klebsiella pneumoniae and Escherichia coli high-risk clones in Catalan healthcare institutions 

    Marí Almirall, Marta; Cosgaya Castro, Clara; Pitart, Cristina; Viñes, Joaquim; Muñoz López, Laura; Campo, Irene; Cuscó, Anna; Rodríguez Serna, Laura; Santana, Gemina; Río, Ana del; Francino, Olga; Ciruela, Pilar; Pujol, Isabel; Ballester, Frederic; Marco, Francesc; Martínez Hernández, José Alfredo; Soriano Viladomiu, Alex; Vila Estapé, Jordi; Roca Subirà, Ignasi; MERCyCAT Study Group (Fecha de publicación: 2023-12-11)

    Objectives: To characterize the clonal spread of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli isolates between different healthcare institutions in Catalonia, Spain. Methods: Antimicrobial susceptibility ...

    Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in cohort of 35 infected fetuses. 

    Hawkins-Villarreal, Ameth; Castillo, Karen; Nadal Serra, Alfons; Planas i Marcé, Sílvia, 1965-; Moreno Espinosa, Ana L.; Alarcón, Ana; Rebollo Polo, Mónica; Figueras Retuerta, Francesc; Gratacós Solsona, Eduard; Eixarch Roca, Elisenda; Goncé Mellgren, Anna (Fecha de publicación: 2024-02-05)

    To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.

    Genotypic and phenotypic study of antiviral resistance mutations in refractory cytomegalovirus infection 

    Santos Bravo, Marta; Nicolas Plault; Sánchez Palomino, Sonsoles; Rodríguez, Cristina; Navarro Gabriel, Mireia; Mosquera, María Mar; Fernández Avilés, Francesc; Suarez Lledó, María; Rovira, Montserrat; Bodro, Marta; Moreno Camacho, Ma. Asunción; Linares, Laura; Cofán Pujol, Federico; Berengua, Carla; Esteva, Cristina; Cordero, Elisa; Martín Dávila, Pilar; Aranzamendi, Maitane; Pérez Jiménez, Ana Belén; Vidal, Elisa; Fernández Sabé, Núria; Len, Óscar; Hantz, Sebastien; Alain, Sophie; Marcos, Ma. Angeles; the Spanish Network for Research in Infectious Diseases (REIPI); Group for the Study of Infection in Transplantation (GESITRA) (Fecha de publicación: 2023-12-04)

    Background This study describes the genotypic and phenotypic characterization of novel human cytomegalovirus (HCMV) genetic variants of a cohort of 94 clinically resistant HCMV patients. Methods and results ...

    IGLV3-21R110 mutation has prognostic value in patients with treatment-naive chronic lymphocytic leukemia 

    Syrykh, Charlotte; Pons-Brun, Berta; Russiñol, Núria; Playa-Albinyana, Heribert; Baumann, Tycho; Duran Ferrer, Martí; Kulis, Marta; Carbó-Meix, Anna; Mozas, Pablo; Alcoceba, Miguel; González, Marcos; Navarro-Bailón, Almudena; Colado, Enrique; Payer, Ángel R; Aymerich Gregorio, Marta; Terol, María J; Lu, Junyan; Knisbacher, Binyamin A; Hahn, Cynthia K; Ruiz-Gaspà, Sílvia; Enjuanes, Anna; Wu, Catherine J; Getz, Gad; Zenz, Thorsten; López Guillermo, Armando; Martín-Subero, José Ignacio; Colomer Pujol, Dolors; Delgado González, Julio; Campo Güerri, Elias; Nadeu Prat, Ferran (Fecha de publicación: 2025-10-14)

    Chronic lymphocytic leukemia (CLL) has high biological and clinical heterogeneity. 1,2 A few prognostic factors are used in clinical practice, including immunoglobulin heavy-chain variable (IGHV) gene somatic hypermutation ...

    Validation of an automatic dose injection system for Ictal SPECT in epilepsy 

    Setoain Perego, Xavier; Pavía Segura, Javier; Serés, Eulàlia; Garcia, Ramiro; Carreño, Mar; Donaire Pedraza, Antonio Jesús; Rubí Sureda, Sebastià; Bargalló Alabart, Núria; Rumià, Jordi; Boget Llucià, Teresa; Pintor Pérez, Luis; Fuster Pelfort, David; Pons Pons, Francisca (Fecha de publicación: 2013-02-07)

    The purpose of our study was to evaluate the performance and clinical usefulness of an automated injector system (AIS) that administers an automated injection for ictal SPECT after calculating the volume of tracer to be ...

    Los antecedentes de la pedagogía vocal contemporánea: el caso del Dr. Ricardo Botey 

    Alessandroni Betancor, Nicolás; Torres, Begoña (Fecha de publicación: 2015-12-10)

    En los estudios históricos sobre Pedagogía Vocal suele situarse al año 1950 como inicio del período de la Pedagogía Vocal Contemporánea, pues ese fue el momento histórico en que diferentes profesionales (maestros de canto, ...

    Picnodisóstosis 

    Querol, X.; Moreno Caballud, Ana; Corretger, J.M.; Fernández, C.; Pastor Durán, Xavier (Fecha de publicación: 2014-12-02)

    Lactante varón de seis meses de edad que consulta por retraso de crecimiento manifiesto desde los cuatro meses. Antecedentes familiares. Primera gestación de padres jóvenes no consanguíneos. Antecedentes personales.Embarazo ...

    Informática en Pediatría: aplicaciones prácticas 

    Pastor Durán, Xavier (Fecha de publicación: 2014-11-05)

    INFORMACION E INFORMATICA La evolución del ser humano se ha comparado a una espiral ascendente cuyo radio es cada vez menor, queriendo simbolizar con ella el incremento en la velocidad con la que se adquieren nuevas ...

    Prevalence and Diagnosis of Latent Tuberculosis Infection in Young Children in the Absence of a Gold Standard 

    Pérez-Porcuna, Tomàs M.; Pereira da Silva, Hélio Doyle; Ascaso Terrén, Carlos; Malheiro, Adriana; Bührer-Sékula, Samira, 1955-; Martínez Espinosa, Flor E.; Abellana Sangrà, Rosa Mari (Fecha de publicación: 2017-07-12)

    Introduction For adequate disease control the World Health Organization has proposed the diagnosis and treatment of latent tuberculous infection (LTBI) in groups of risk of developing the disease such as children. There ...

    High prevalence and mortality due to Histoplasma capsulatum in the Brazilian Amazon: An autopsy study 

    Rakislova, Natalia; Hurtado, Juan Carlos; Palhares, Antonio E. M.; Ferreira, Luiz C. L.; Freire, Monique; Lacerda, Marcus Vinícius Guimarães; Monteiro, Wuelton Marcelo; Navarro, Mireia; Casas, Isaac; Teixeira, Marcus de Melo; Castillo, Paola; Rodrigo Calvo, María Teresa; Marimon, Lorena; Guerrero, José; Varo, Rosauro; Delgado, Vima; Quintó, Llorenç; Marco Reverté, Francesc; Letang, Emilio; Vila Estapé, Jordi; Bassat Orellana, Quique; Menéndez, Clara; Ordi i Majà, Jaume; Martínez Yoldi, Miguel Julián (Fecha de publicación: 2021-04-28)

    Background: Histoplasmosis is acquired by inhalation of spores of the dimorphic fungus Histoplasma spp. Although this pathogen is distributed worldwide, it is more prevalent in the Americas. However, the real burden of ...

    Síndrome Guillain Barré y ausencia de IgA 

    Roca, A.; Molinero, C.; Pastor Durán, Xavier; Palomeque, A. (Fecha de publicación: 2014-12-02)

    Introducción El síndrome Guillain-Barré se caracteriza por la presencia de una polirradiculoneuropatía aguda, rápidamente progresiva y simétrica, con afectación predominante de la función motora, y que suele acompañarse ...

    Efficacy of the fluorescent dyes Fast Blue, Fluoro-Gold, and Diamidino Yellow for retrograde tracing to dorsal root ganglia after subcutaneous injection 

    Puigdellívol Sánchez, Anna; Prats Galino, Alberto; Ruano Gil, Domingo; Molander, Carl (Fecha de publicación: 2014-09-05)

    The present study was designed to investigate the efficacy of the fluorescent dyes Fast Blue (FB), Fluoro-Gold (FG), and Diamidino Yellow (DY) for retrograde tracing of lumbar dorsal root ganglia after their subcutaneous ...