Institut de Recerca en Sistemes Complexos (UBICS): Enviaments recents
Ara mostrant els elements 101-118 de 118
Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks
Recent progress in the field of human induced pluripotent stem cells (iPSCs) has led to the efficient production of human neuronal cell models for in vitro study. This has the potential to enable the understanding of live ...
Aproximacions a la perspectiva de la persona en tractament de manteniment amb metadona: Reflexions a propòsit de 10 anys de recerca
Els tractaments de manteniment amb metadona (TMM) són un autèntic tractament psicofarmacològic de la dependència d'heroïna i, a la vegada, un element indispensable de les polítiques i les intervencions de reducció de danys. ...
Complex systems representing effective connectivity in patients with Type One diabetes mellitus
Background Type 1 diabetes mellitus (T1D) affects the entire cellular network of the organism. Some patients develop cognitive disturbances due to the disease, but several authors have suggested that the brain develops ...
Transport and Assembly of Magnetic Surface Rotors
This minireview focuses on recent advances with surface magnetic rotors, namely field-responsive spherical or anisotropic microparticles that translate close to, or are embedded in a confining surface. The application of ...
COLONOMICS - integrative omics data of one hundred paired normal-tumoral samples from colon cancer patients
Colonomics is a multi-omics dataset that includes 250 samples: 50 samples from healthy colon mucosa donors and 100 paired samples from colon cancer patients (tumor/adjacent). From these samples, Colonomics project includes ...
First Order Alignment Transition in an Interfaced Active Nematic
We investigate experimentally the dynamic phase transition of a two-dimensional active nematic layer interfaced with a passive liquid crystal. Under a temperature ramp that leads to the transition of the passive liquid ...
Formation of metastable phases by spinodal decomposition
Metastable phases may be spontaneously formed from other metastable phases through nucleation. Here we demonstrate the spontaneous formation of a metastable phase from an unstable equilibrium by spinodal decomposition, ...
Multicaloric effects and magnetostructural coupling in the Cr2Ge2Te6 van der Waals crystal
Materials with significant coupling between magnetism and their crystal structure are prone to exhibit multicaloric effects, which offer a novel approach to addressing the bottlenecks of ecologic solid-state refrigeration ...
Topological Boundary Constraints in Artificial Colloidal Ice
The effect of boundaries and how these can be used to influence the bulk behavior in geometrically frustrated systems are both long-standing puzzles, often relegated to a secondary role. Here, we use numerical simulations ...
Enhanced diffusion and non-Gaussian dynamics in driven magnetic nanoparticles
We investigate the out-of-equilibrium dynamics of paramagnetic colloidal nanoparticles driven above a triangular lattice of cylindrical ferromagnetic domains. We use an external precessing magnetic field to create a dynamic ...
Hydrodynamic Interactions Can Induce Jamming in Flow-Driven Systems
Hydrodynamic interactions between fluid-dispersed particles are ubiquitous in soft matter and biological systems and they give rise to intriguing collective phenomena. While it was reported that these interactions can ...
Laning, thinning and thickening of sheared colloids in a two-dimensional Taylor-Couette geometry
We investigate the dynamics and rheological properties of a circular colloidal cluster that is continuously sheared by magnetic and optical torques in a two-dimensional (2D) Taylor-Couette geometry. By varying the two ...
Aggregation of discoidal particles due to depletion interaction
Depletion interactions between colloids of discoidal shape can induce their self-assembly into columnar aggregates. This is an effect of entropic origin with important implications in a range of colloidal systems, particularly ...
Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration
A deeper understanding of early disease mechanisms occurring in Parkinson's disease (PD) is needed to reveal restorative targets. Here we report that human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons ...
Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability
Background Cellular prion protein (PrP(C)) is a cell surface GPI-anchored protein, usually known for its role in the pathogenesis of human and animal prionopathies. However, increasing knowledge about the participation of ...
Comparison between 16S rRNA and shotgun sequencing in colorectal cancer, advanced colorectal lesions, and healthy human gut microbiota
Background: Gut dysbiosis has been associated with colorectal cancer (CRC), the third most prevalent cancer in the world. This study compares microbiota taxonomic and abundance results obtained by 16S rRNA gene sequencing ...
Human pluripotent stem cell-derived neurons are functionally mature in vitro and integrate into the mouse striatum following transplantation
Human Pluripotent Stem Cells (hPSCs) are a powerful tool for modelling human development. In recent years, hPSCSs have become central in cell-based therapies for neurodegenerative diseases given their potential to replace ...
Exploring Food Addiction Across Several Behavioral Addictions: Analysis of Clinical Relevance
Background/Objectives: Recently, interest in studying food addiction (FA) in the context of behavioral addictions (BAs) has increased. However, research remains limited to determine the FA prevalence among various BAs. The ...
