Química Inorgànica i Orgànica: Envíos recientes
Mostrando ítems 701-720 de 1016
Tuning Single-Molecule Conductance in Metalloporphyrin-Based Wires via Supramolecular Interactions.
Nature has developed amazing supramolecular constructs to deliver outstanding charge transport capabilities using metalloporphyrin-based supramolecular stacks.1 Here we are incorporating simple, naturally inspired ...
Rational optimization of a transcription factor activation domain inhibitor
Transcription factors are among the most attractive therapeutic targetsbut are considered largely ‘undruggable’ in part due to the intrinsicallydisordered nature of their activation domains. Here we show that thearomatic ...
Multi-Length Scale Communication Effects in Catalysis: Thinking Big and Acting Small
The use of hierarchically structured materialsas catalysts has been finding increasing applicationin the past years. For these catalytic systems, notonly the nano-scale matters: a high degree of orderacross multiple length ...
Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations
Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we kinetically and mechanistically describe the ...
Thiocoumarin-based Au(I) Complexes and Au(0) Systems over TiO2 as Hybrid Photocatalysts for Hydrogen Generation under UV–Vis Light
This work focuses on the photocatalytic production of hydrogen from the photodehydrogenation of ethanol using several gold(I) complexes and gold(0) systems over titanium dioxide (P90 TiO2) as hybrid photocatalysts. The ...
Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug. (-)-C75 has antitumour activity
C75 is a synthetic compound described as having antitumoral properties. It produces hypophagia and weight loss in rodents, limiting its use in cancer therapy but identify- ing it as a potential anti-obesity drug. C75 is a ...
Encapsulation of a CrIII single-ion magnet within an FeII spin-crossover supramolecular host
Single functional molecules are regarded as future components of nanoscale spintronic devices. Supramolecular coordination chemistry provides unlimited resources to implement multiple functions to individual molecules. A ...
Unravelling the elusive antiferromagnetic order in wurtzite and zinc blende CoO polymorph nanoparticles
Although cubic rock salt‐CoO has been extensively studied, the magnetic properties of the main nanoscale CoO polymorphs (hexagonal wurtzite and cubic zinc blende structures) are rather poorly understood. Here, a detailed ...
Solid-state organization of n-type carbazole-based semiconductors for organic thin-film transistors
The development of new organic semiconductors has been mainly led by the search for new π-conjugated cores, but recently the use of flexible side chains is attracting more and more attention to control the molecular packing ...
Structure, magnetic properties and DFT calculations of azido-copper(II) complexes with different azido-bonding, nuclearity and dimensionality
Four bridged-azido Cu(II) complexes were synthesized and structurally characterized: [Cu-2(Et(3)en)(2)(mu(1,1)-N-3)(2)(N-3)(2)] (1), [Cu-2(ip(2)en)(2)(mu(1,1)-N-3)(2)(N-3)(2)] (2), catena-[Cu-2(Et(2)Meen)(2)(mu(1,3)-N-3)(3)]ClO4 ...
A setup to measure the temperature-dependent heating power of magnetically heated nanoparticles up to high temperature.
Magnetic heating, namely, the use of heat released by magnetic nanoparticles (MNPs) excited with a high-frequency magnetic field, has so far been mainly used for biological applications. More recently, it has been shown ...
Environment-responsive Pt(II) complexes boost aggregation-enhanced emission and singlet oxygen production
Here, we introduce an environment-tuning strategy to simultaneously boost aggregation-enhanced emission (AEE) and singlet oxygen (1O2) generation in PEGylated platinum(II) pyridyl complexes. Different amphiphilic Pt(II) ...
The impact of the hydroxymethylcytosine epigenetic signature on DNA structure and function
We present a comprehensive, experimental and theoretical study of the impact of 5-hydroxymethylation of DNA cytosine. Using molecular dynamics, biophysical experiments and NMR spectroscopy, we found that Ten-Eleven ...
Proteomic tools for the quantitative analysis of artificial peptide libraries: detection and characterization of target-amplified PD-1 inhibitors
We report a quantitative proteomics data analysis pipeline which, coupled to protein-directed dynamic combinatorial chemistry (DDC) experiments, enables the rapid discovery and direct characterization of protein-protein ...
Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery
Brain delivery is one of the major challenges in drug development because of the high number of patients suffering from neural diseases and the low efficiency of the treatments available. Although the blood-brain barrier ...
A first-principles analysis of the magnetism of CuII polynuclear coordination complexes: the case of [Cu4(bpy)4(aspartate)2(H2O)3](ClO4)4·2.5H2O
The magnetic structure of the [Cu4(bpy)4(aspartate)2(H2O)3](ClO4)4·2.5 H2Ocrystal - using fractional coordinates determined at room-temperature ¿ has beenanalysed in detail. This analysis has been carried out by extending ...
Low-dimensional polynuclear complexes and high-spin molecules: towards molecules magnets
[eng] Coordination chemistry allows the synthesis of new molecules which show cooperative magnetic phenomena, behaving like magnets. Two main ways of synthesizing these systems have been developed: a) low-dimensional ...
An intrinsically disordered region of RPN10 plays a key role in restricting ubiquitin chain elongation in RPN10 monoubiquitination
Dissolution dynamic nuclear polarization (DNP) has become one of the predominant implementations for DNP. However, the technical implementation of transferring the sample from the polarizer to the nuclear magnetic resonance ...
Nivell en competències bàsiques dels estudiants del grau de química de la Universitat de Barcelona. Correspondència amb les qualificacions d'accés i del grau.
INTRODUCCIÓ. Les competències en raonament matemàtic, raonament lògic, raonament geometricoespacial i pensament crític són fonamentals en qualsevol ensenyament superior científic o tecnològic i, en particular, en un grau ...
Ligand and Gold(I) Fluorescein−AIEgens as Photosensitizers in Solution and Doped Polymers
The synthesis of fluorescein propargyl diether (L) and two different dinuclear gold(I) derivatives containing a water-soluble phosphane [1,3,5-triaza-7-phosphatricyclo[3.3.1.13.7]decane (PTA) for complex 1 and 3,7-diacet ...
