Novel end-to-end services are expected to emerge with the advent of 5G. In order to satisfy QoS/QoE requirements (e.g., lower latency, higher traffic volume and dynamicity, or availability) of those services, major changes on the network architecture are required. Technologies such as SDN and NFV, in conjunction with the edge-computing paradigm facilitate this transition, enabling the presence of cloud-enabled systems on mobile radio access networks. In this paper, we present a novel approach to handle Service Chaining handover, leveraging a joint orchestration between NFV and RAN domains.