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Somatostatin receptor-targeted organometallic iridium(III) complexes as novel theranostic agents

Author

Novohradsky, Vojtech

Zamora, Ana

Gandioso, Albert

Brabec, Viktor

Ruiz, José

Marchán Sancho, Vicente

Publication date

2017-07-10T10:15:57Z

2017-07-10T10:15:57Z

2017-04-25

2017-07-10T10:15:57Z

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Abstract

A novel somatostatin receptor-targeted anticancer agent based on the conjugation of a highly cytotoxic and luminiscent cyclometalated iridium(III) complex to tumor-targeting vectors based on octreotide peptide has been described, and its potential for targeted theranostic applications has been demonstrated.

Document Type

Article

Published version

Language

English

Subjects and keywords

Iridi; Càncer; Somatostatina; Iridium; Cancer; Somatostatin

Publisher

Royal Society of Chemistry

Related items

Reproducció del document publicat a: https://doi.org/10.1039/c7cc01946g

Chemical Communications, 2017, vol. 53, p. 5523-5526

https://doi.org/10.1039/c7cc01946g

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Rights

cc-by (c) Novohradsky, Vojtech et al., 2017

http://creativecommons.org/licenses/by/3.0/es

This item appears in the following Collection(s)

ISGlobal - Institut de Salut Global de Barcelona [61308]

Química Inorgànica i Orgànica [1012]