Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study

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RECERCAT Home > Universitat de Barcelona > IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer > Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) > View document

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dc.contributor.author	Carugati, Manuela
dc.contributor.author	Aliberti, Stefano
dc.contributor.author	Reyes, Luis F.
dc.contributor.author	Franco Sadud, Ricardo
dc.contributor.author	Irfan, Muhammad
dc.contributor.author	Prat, Cristina
dc.contributor.author	Soni, Nilam J.
dc.contributor.author	Faverio, Paola
dc.contributor.author	Gori, Andrea
dc.contributor.author	Blasi, Francesco
dc.contributor.author	Restrepo, Marcos I.
dc.contributor.author	Cillóniz, Catia
dc.contributor.author	Torres Martí, Antoni
dc.contributor.author	GLIMP collaborators
dc.date	2019-07-09T11:12:12Z
dc.date	2019-07-09T11:12:12Z
dc.date	2018-10-04
dc.date	2019-07-02T19:44:26Z
dc.identifier	2312-0541
dc.identifier	5635448
dc.identifier	30474036
dc.identifier.uri	http://hdl.handle.net/2445/136714
dc.description	This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.
dc.format	13 p.
dc.format	application/pdf
dc.language	eng
dc.publisher	European Respiratory Society
dc.relation	Reproducció del document publicat a: https://doi.org/10.1183/23120541.00096-2018
dc.relation	ERJ Open Research, 2018, vol. 4, num. 4
dc.relation	https://doi.org/10.1183/23120541.00096-2018
dc.rights	cc by-nc (c) ERS, 2018
dc.rights	http://creativecommons.org/licenses/by-nc/3.0/es/
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	Pneumònia adquirida a la comunitat
dc.subject	Microbiologia mèdica
dc.subject	Community-acquired pneumonia
dc.subject	Medical microbiology
dc.title	Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion

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