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| dc.contributor.author | López Pelayo, Hugo |
|---|---|
| dc.contributor.author | Miquel de Montagut, Laia |
| dc.contributor.author | Altamirano, José |
| dc.contributor.author | Bataller Alberola, Ramón |
| dc.contributor.author | Caballeria Rovira, Joan |
| dc.contributor.author | Ortega, Lluisa |
| dc.contributor.author | Lligoña, Anna |
| dc.contributor.author | Gual, Antoni |
| dc.date | 2020-03-03T15:35:09Z |
| dc.date | 2020-03-03T15:35:09Z |
| dc.date | 2019-01-01 |
| dc.date | 2020-03-03T15:35:09Z |
| dc.identifier | 0022-3999 |
| dc.identifier | 689864 |
| dc.identifier.uri | http://hdl.handle.net/2445/151828 |
| dc.description | Aims: Alcoholic hepatitis (AH) is a life-threatening complication of alcohol use disorder (AUD). Alcohol abstinence is the main predictor of the long-term prognosis of AH. It is unknown whether AUD treatment retention (TR) after an AH episode impacts alcohol relapse and mortality or what baseline factors influence TR. Methods: Design: case-control study; Study population: hospitalized patients (1999-2012) with an episode of biopsy-proven AH were included (n = 120); Assessment: demographic and clinical data, the High-Risk Alcoholism Relapse (HRAR) scale, mortality and alcohol relapse were assessed through clinical records and telephone or personal interviews; Follow-up period: short-term and long-term TRs were assessed at 12 and 24 months, respectively. Results: The overall short-term and long-term TRs were 37% and 27.8%, respectively. The severity of liver disease at baseline predicted both short-term and long-term TR (OR 3.7 and 3.3, respectively), whereas HRAR >3 and a history of psychiatric disorders predicted long-term TR (OR 2.9 and 2.6, respectively). Moreover, HRAR >3 (OR 3.0) and previous treatment for AUD (OR 2.9) increased the risk of relapse in the short term. Importantly, receiving alcohol therapy in a centre different from the hospital where the patient was admitted was associated with increased risk of alcohol relapse over the long term (OR 5.4). Conclusion: Experiencing an alcohol-related life-threatening complication is insufficient motivation to seek treatment for AUD. AUD treatment after an episode of AH is suboptimal, with a low TR rate, high risk of alcohol relapse and poor impact of treatment on alcohol relapse. |
| dc.format | 8 p. |
| dc.format | application/pdf |
| dc.language | eng |
| dc.publisher | Elsevier B.V. |
| dc.relation | Versió postprint del document publicat a: https://doi.org/10.1016/j.jpsychores.2018.11.020 |
| dc.relation | Journal of Psychosomatic Research, 2019, vol. 116, p. 75-82 |
| dc.relation | https://doi.org/10.1016/j.jpsychores.2018.11.020 |
| dc.rights | cc-by-nc-nd (c) Elsevier B.V., 2019 |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/es |
| dc.rights | info:eu-repo/semantics/openAccess |
| dc.subject | Hepatitis |
| dc.subject | Consum d'alcohol |
| dc.subject | Hepatitis |
| dc.subject | Drinking of alcoholic beverages |
| dc.title | Treatment retention in a specialized alcohol programme after an episode of alcoholic hepatitis: Impact on alcohol relapse |
| dc.type | info:eu-repo/semantics/article |
| dc.type | info:eu-repo/semantics/acceptedVersion |
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