Universitat de Barcelona
2020-04-16T10:18:45Z
2020-04-16T10:18:45Z
2018-12-03
2020-04-16T10:18:45Z
The effect of resveratrol (RV) intake has been reviewed in several studies performed in humans with different health status. The purpose of this review is to summarize the results of clinical trials of the last decade, in which RV was determined in biological samples such as human plasma, urine, and feces. The topics covered include RV bioavailability, pharmacokinetics, effects on cardiovascular diseases, cognitive diseases, cancer, type 2 diabetes (T2D), oxidative stress, and inflammation states. The overview of the recent research reveals a clear tendency to identify RV in plasma, showing that its supplementation is safe. Furthermore, RV bioavailability depends on several factors such as dose, associated food matrix, or time of ingestion. Notably, enterohepatic recirculation of RV has been observed, and RV is largely excreted in the urine within the first four hours after consumption. Much of the research on RV in the last 10 years has focused on its effects on pathologies related to oxidative stress, inflammatory biomarkers, T2D, cardiovascular diseases, and neurological diseases
Article
Published version
English
Biodisponibilitat; Obesitat; Trastorns del metabolisme; Antioxidants; Farmacologia; Bioavailability; Obesity; Disorders of metabolism; Antioxidants; Pharmacology
MDPI
Reproducció del document publicat a: https://doi.org/10.3390/nu10121892
Nutrients, 2018, vol. 10, num. 12, p. 1892
https://doi.org/10.3390/nu10121892
cc-by (c) Ramírez-Garza, Sonia L. et al., 2018
http://creativecommons.org/licenses/by/3.0/es
