Universitat de Barcelona
2020-04-27T11:59:00Z
2020-04-27T11:59:00Z
2017-03-18
2020-04-27T11:59:00Z
A critical summary on the discovery of the nineteen members of the phakellistatin family (phakellistatin 1-19), cytotoxic proline‐rich cyclopeptides of marine origin, is reported. Isolation, structural elucidation, and biological properties of the various‐sized natural macrocycles are described, along with the total syntheses and the enigmatic issues of the cytotoxic activity reproducibility.
Article
Published version
English
Aminoàcids; Síntesi de pèptids; Farmacologia; Amino acids; Peptide synthesis; Pharmacology
MDPI
Reproducció del document publicat a: https://doi.org/10.3390/md15030078
Marine Drugs, 2017, vol. 15, num. 3, p. 78
https://doi.org/10.3390/md15030078
info:eu-repo/grantAgreement/EC/FP7/319011/EU//POMOS
cc-by (c) Meli, Alessandra et al., 2017
http://creativecommons.org/licenses/by/3.0/es
