2020-06-03T09:40:22Z
2020-06-03T09:40:22Z
2012-01-06
2020-06-03T09:40:22Z
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams.
Article
Accepted version
English
Síntesi orgànica; Lactames; Enantiòmers; Compostos heterocíclics; Organic synthesis; Lactams; Enantiomers; Heterocyclic compounds
American Chemical Society
Versió postprint del document publicat a: https://doi.org/10.1021/ol2030058
Organic Letters, 2012, vol. 14, num. 1, p. 210-213
https://doi.org/10.1021/ol2030058
(c) American Chemical Society , 2012