Cost-effectiveness of insulin degludec versus insulin glargine U100 in patients with type 1 and type 2 diabetes in Portugal: evidence from SWITCH 1&2 trials

Publication date

2020-06-10T08:05:43Z

2020-12-20T06:10:18Z

2019-12-20

2020-06-10T08:05:43Z

Abstract

Objectives: To assess the cost-effectiveness of insulin degludec (degludec) versus insulin glargine (glargine) U100 from a Portuguese healthcare perspective using data from SWITCH 1 & 2 trials. - - - Methods: A short-term model estimated cost-effectiveness of degludec versus glargine U100 in type 1 diabetes (T1DM) basal bolus (B/B) and type 2 diabetes (T2DM) basal oral therapy (BOT) patients. The model captured hypoglycaemia rates and insulin dosing. Clinical outcomes were obtained from SWITCH 1 & 2. Disutilities related to hypoglycaemic events and insulin, needles and blood glucose tests costs were also included. Benefits were measured in QALYs. One-way and probabilistic sensitivity analyses were conducted (...)

Document Type

Article


Accepted version

Language

English

Publisher

Cortex - Publicacoes Tecnicas e Cientificas

Related items

Versió postprint del document publicat a: http://www.revportdiabetes.com/rpd-dez-2019/

Revista Portuguesa de Diabetes, 2019, vol. 14, num. 4, p. 141-150

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cc-by-nc-nd (c) Cortex - Publicacoes Tecnicas e Cientificas, 2019

http://creativecommons.org/licenses/by-nc-nd/3.0/es

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