Controlling shapes in a coaxial focusing microfluidic device: experiments and theory

Publication date

2021-02-08T12:15:01Z

2021-02-08T12:15:01Z

2020-01-13

2021-02-08T12:15:01Z

Abstract

A coaxial flow focusing PDMS (polydimethylsiloxane) microfluidic device has been designed and manufactured by soft lithography in order to experimentally study a miscible inner flow. We studied a coaxially focused inner flow (formed by an aqueous fluorescein solution) which was fully isolated from all microchannel surfaces by an additional water outer flow. Different flow rates were used to produce a variety of flow ratios and a 3D reconstruction of the cross-section was performed using confocal microscope images. The results showed an elliptical section of the coaxially focused inner flow that changes in shape depending on the flow rate ratio applied. We have also developed a mathematical model that allows us to predict and control the geometry of the coaxially focused inner flow.

Document Type

Article


Published version

Language

English

Publisher

MDPI

Related items

Reproducció del document publicat a: https://doi.org/10.3390/mi11010085

Micromachines, 2020, vol. 11, num. 85

https://doi.org/10.3390/mi11010085

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Rights

cc-by (c) Rodriguez Trujillo, Romen et al., 2020

http://creativecommons.org/licenses/by/3.0/es