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Microglia is an active player in how glibenclamide improves stroke outcome

Author

Ortega González, Fco. Javier

Jolkkonen, Jukka

Rodríguez Allué, Manuel José

Publication date

2014-09-26T08:04:03Z

2013-05-01

2014-09-26T08:04:03Z

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Abstract

The recent review article"Sulfonylurea receptor 1 in central nervous system injury: a focused review"1 is an extensive summary of the current knowledge of the role of the sulfonylurea receptor 1 (SUR-1) and SUR-1-regulated NCCa-ATP channels in acute brain injuries. The review also highlights the potential translational applicability of the use of glibenclamide in treating brain pathologies such as cerebral ischemia or traumatic brain injury.......

Document Type

Article

Accepted version

Language

English

Subjects and keywords

Isquèmia cerebral; Micròglia; Cerebral ischemia; Microglia

Publisher

International Society for Cerebral Blood Flow and Metabolism

Related items

http://dx.doi.org/10.1038/jcbfm.2013.72

Journal of Cerebral Blood Flow and Metabolism, 2013, vol. 33, num. 7, p. 1138-1139

http://dx.doi.org/10.1038/jcbfm.2013.72

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Rights

(c) Ortega, F.J. et al., 2013

This item appears in the following Collection(s)

Ciències Fisiològiques [824]

ISGlobal - Institut de Salut Global de Barcelona [61307]