Editorial: Mucosal immunity after vaccination

Abstract

The mucosal immune system is the largest immunological interface with the environment in our body. On the one hand, it contributes to the preservation of commensal microbiota by several mechanisms such production of secretory immunoglobulins, maintenance of the mucus layer, mucosal cell signaling -via production of cytokines, and chemokines-, or tolerance via regulatory T-cells, among others. On the other hand, the mucosal immune serves as both a barrier and an active immunological network that protects against pathogen invasion at entry sites. This Research Topic "Mucosal Immunity after Vaccination" in Frontiers in Immunology brings together six studies spanning human health, veterinary medicine, and experimental vaccine platforms. Collectively, it illustrates how diverse strategies from metabolic optimization to innovative delivery systems can converge on the goal of robust mucosal immunity after vaccination