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dc.contributor | Universitat de Barcelona |
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dc.contributor.author | Alemany Sierra, Silvia |
dc.contributor.author | Goldberg, Ximena |
dc.contributor.author | Van Winkel, R. |
dc.contributor.author | Gastó Ferrer, Cristóbal |
dc.contributor.author | Peralta, V. |
dc.contributor.author | Fañanás Saura, Lourdes |
dc.date | 2013-10-10T12:40:11Z |
dc.date | 2013-10-10T12:40:11Z |
dc.date | 2013-05 |
dc.date | 2013-10-10T12:40:11Z |
dc.identifier.citation | 0924-9338 |
dc.identifier.citation | 612345 |
dc.identifier.uri | http://hdl.handle.net/2445/46846 |
dc.description.abstract | Purpose: To test whether the association between childhood adversity and positive and negative psychotic experiences is due to genetic confounding. Method: Childhood adversity and psychotic experiences were assessed in a sample of 226 twins from the general population. A monozygotic (MZ) twin differences approach was used to assess possible genetic confounding. Results: In the whole sample, childhood adversity was significantly associated with positive (β =.45; SE=.16; p=.008) and negative psychotic experiences (β=.77; SE=.18; p<.01). Within-pair MZ twin differences in exposure to childhood adversity were significantly associated with differences in positive (β =.71; SE=.29; p=.016) and negative psychotic experiences (β =.98; SE=.38; p=.014) in a subsample of 86 MZ twin pairs. Conclusions: Individuals exposed to childhood adversity are more likely to report psychotic experiences. Furthermore, our findings indicate that unique environmental effects of childhood adversity contribute to the development of psychotic experiences. |
dc.format | 22 p. |
dc.format | application/pdf |
dc.language.iso | eng |
dc.publisher | Elsevier Masson SAS |
dc.relation | Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.eurpsy.2012.03.001 |
dc.relation | European Psychiatry, 2013, vol. 28, num. 4, p. 207-212 |
dc.relation | http://dx.doi.org/10.1016/j.eurpsy.2012.03.001 |
dc.rights | (c) Elsevier Masson SAS, 2013 |
dc.rights | info:eu-repo/semantics/openAccess |
dc.subject | Genètica |
dc.subject | Psicopatologia infantil |
dc.subject | Esquizofrènia |
dc.subject | Infants maltractats |
dc.subject | Genetics |
dc.subject | Child psychopathology |
dc.subject | Schizophrenia |
dc.subject | Abused children |
dc.title | Childhood adversity and psychosis: examinig whether the association is due to genetic confounding using a monozygotic twin differences approach |
dc.type | info:eu-repo/semantics/article |
dc.type | info:eu-repo/semantics/acceptedVersion |