dc.contributor.author |
Echavarren, Antonio M. |
dc.contributor.author |
Dorel, Ruth |
dc.contributor.author |
Muratore, Michael E. |
dc.contributor.author |
Kirillova, Mariia S. |
dc.date.accessioned |
2018-06-15T11:41:03Z |
dc.date.available |
2018-06-15T11:41:03Z |
dc.date.issued |
2016-03-10 |
dc.identifier.uri |
http://hdl.handle.net/2072/326397 |
dc.format.extent |
3671 p. |
dc.language.iso |
eng |
dc.publisher |
J. Am. Chem. Soc. |
dc.rights |
L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.source |
RECERCAT (Dipòsit de la Recerca de Catalunya) |
dc.subject.other |
Quimica |
dc.title |
Concise Total Synthesis of Lundurines A−C Enabled by Gold Catalysis and a Homodienyl Retro-Ene/Ene Isomerization |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/draft |
dc.embargo.terms |
cap |
dc.identifier.doi |
10.1021/jacs.6b01428 |
dc.rights.accessLevel |
info:eu-repo/semantics/openAccess |
dc.description.abstract |
The total synthesis of lundurines A–C has been accomplished in racemic and enantiopure forms in 11–13 and 12–14 steps, respectively, without protection/deprotection of functional groups, by a novel tandem double condensation/Claisen rearrangement, a gold(I)-catalyzed alkyne hydroarylation, a cyclopropanation via formal [3 + 2] cycloaddition/nitrogen extrusion, and a remarkable olefin migration through a vinylcyclopropane retro-ene/ene reaction that streamlines the endgame. |