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Título:	Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
Autor/a:	Mas‐Stachurska, Aleksandra; Siegert, Anna‐Maria; Batlle, Montserrat; Gorbenko del Blanco, Darya; Meirelles, Thayna; Rubies, Cira; Bonorino, Fabio; Serra‐Peinado, Carla; Bijnens, Bart; Baudin, Julio; Sitges, Marta; Mont, Lluís; Guasch, Eduard; Egea, Gustavo
Abstract:	Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.
Abstract:	This work was partially supported by grants from the Instituto de Salud Carlos III (PI13/01580, PI16/00703); Sociedad Española de Cardiología; National Marfan Foundation; Ministerio de Economia y Competitividad (SAF2015‐64136R, SAF2017‐83039‐R, TIN2014‐52923‐R); Fondo Europeo de Desarrollo Regional (FEDER); Agència de Gestió d'Ajuts Universitaris i de Recerca (2014SGR334); CERCA Programme/Generalitat de Catalunya and Centro de Investigación Biomédica en RED (CIBERCV 16/11/00354).
Materia(s):	-Vascular disease -Exercise -Aneurysm -Behavioral medicine -Prevention -Basic -Epidemiology -Health -Wellness -Translational -Clinical research -Lifestyle -Prevention -Animal models -Human disease
Derechos:	© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made. https://creativecommons.org/licenses/by-nc-nd/4.0/
Tipo de documento:	Artículo Artículo - Versión publicada
Editor:	Wiley
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