Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model

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dc.contributor.author	Mas‐Stachurska, Aleksandra
dc.contributor.author	Siegert, Anna‐Maria
dc.contributor.author	Batlle, Montserrat
dc.contributor.author	Gorbenko del Blanco, Darya
dc.contributor.author	Meirelles, Thayna
dc.contributor.author	Rubies, Cira
dc.contributor.author	Bonorino, Fabio
dc.contributor.author	Serra‐Peinado, Carla
dc.contributor.author	Bijnens, Bart
dc.contributor.author	Baudin, Julio
dc.contributor.author	Sitges, Marta
dc.contributor.author	Mont, Lluís
dc.contributor.author	Guasch, Eduard
dc.contributor.author	Egea, Gustavo
dc.date	2017
dc.identifier.citation	Mas‐Stachurska A, Siegert AM, Batlle M, Gorbenko del Blanco D, Meirelles T, Rubies C, Bonorino F, Serra‐Peinado C, Baudin J, Sitges M, Mont L, Guasch E, Egea G. Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model. J Am Heart Assoc. 2017;6(9):e006438. DOI: 10.1161/JAHA.117.006438
dc.identifier.citation	2047-9980
dc.identifier.citation	https://dx.doi.org/10.1161/JAHA.117.006438
dc.identifier.uri	http://hdl.handle.net/10230/36956
dc.format	application/pdf
dc.language.iso	eng
dc.publisher	Wiley
dc.relation	Journal of the American Heart Association. 2017;6(9):e006438.
dc.relation	info:eu-repo/grantAgreement/ES/1PE/SAF2015‐64136R
dc.relation	info:eu-repo/grantAgreement/ES/2PE/SAF2017‐83039‐R
dc.relation	info:eu-repo/grantAgreement/ES/1PE/TIN2014‐52923‐R
dc.rights	© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made.
dc.rights	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	Vascular disease
dc.subject	Exercise
dc.subject	Aneurysm
dc.subject	Behavioral medicine
dc.subject	Prevention
dc.subject	Basic
dc.subject	Epidemiology
dc.subject	Health
dc.subject	Wellness
dc.subject	Translational
dc.subject	Clinical research
dc.subject	Lifestyle
dc.subject	Prevention
dc.subject	Animal models
dc.subject	Human disease
dc.title	Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.description.abstract	Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.
dc.description.abstract	This work was partially supported by grants from the Instituto de Salud Carlos III (PI13/01580, PI16/00703); Sociedad Española de Cardiología; National Marfan Foundation; Ministerio de Economia y Competitividad (SAF2015‐64136R, SAF2017‐83039‐R, TIN2014‐52923‐R); Fondo Europeo de Desarrollo Regional (FEDER); Agència de Gestió d'Ajuts Universitaris i de Recerca (2014SGR334); CERCA Programme/Generalitat de Catalunya and Centro de Investigación Biomédica en RED (CIBERCV 16/11/00354).

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