Title:
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Site-Selective, Remote sp3 C-H Carboxylation Enabled by the Merger of Photoredox and Nickel Catalysis
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Author:
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Sahoo, Basudev; Bellotti, Peter; Julià-Hern#ndez, Francisco; Meng, Qing-Yuan; Crespi, Stefano; Kçnig, Burkhard; Martin, Ruben
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Abstract:
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A photoinduced carboxylation of alkyl halides
with CO2 at remote sp3 C@H sites enabled by the merger
of photoredox and Ni catalysis is described. This protocol
features a predictable reactivity and site selectivity that
can be modulated by the ligand backbone. Preliminary
studies reinforce a rationale based on a dynamic displacement
of the catalyst throughout the alkyl side chain. |
Publication date:
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2019-05-09 |
Subject(s):
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54 |
Rights:
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L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Pages:
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9001 p. |
Document type:
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Article Article - Accepted version |
DOI:
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10.1002/chem.201902095
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