IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer

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Els materials de recerca de la Universitat de Barcelona (UB) a RECERCAT s'obtenen de les col·leccions de Recerca del Dipòsit Digital de la UB.
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Política d’accés obert a la UB


Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.

Enviaments recents

Llista ítems afegits recenment

Endocervical Brush Cytology After Cervical Conization as a Predictor of Treatment Failure: A Prospective Cohort Study 

Carreras Diéguez, Nuria; Torras, Ines; Martí Delgado, Cristina; Matas, Isabel; Glickman, Ariel; Fusté, Pere; Mula, Cristina; Alos, Silvia; Hoya, Sandra; Rakislova, Natalia; Saco, Adela; Marimon, Lorena; Ordi i Majà, Jaume; Torné Bladé, Aureli; Pino Saladrigues, Marta del (Data de publicació: 2026-04-10)

Objective Endocervical curettage (ECC) is the gold standard for predicting the persistence of high-grade squamous intraepithelial lesions (HSIL) after cervical conization. However, ECC has a high rate of unsatisfactory ...

Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations 

Marin, Concepció; Alobid, Isam; López Chacón, Mauricio; Rodriguez-Van Strahlen, Camilo; Mullol i Miret, Joaquim (Data de publicació: 2026-04-10)

Purpose of review: Neurogenesis occurring in the olfactory epithelium is critical to continuously replace olfactory neurons to maintain olfactory function, but is impaired during chronic type 2 and non-type 2 inflammation ...

Standard or Fin SIGN® nail? which option is better for the treatment of femoral fractures in low and middle-income countries? 

Perdomo Lizarraga, Juan Carlos; Andrade Arellano, Dennys J.; Necchi, Marco; Zavatta, Marcello; Ryan Coker, Marcella F. D.; Dixon Cole, Richmond; Muñoz Mahamud, Ernesto; Combalía Aleu, Andrés (Data de publicació: 2026-04-09)

Purpose Femoral fractures are common in low and middle-income countries (LMIC), predominantly caused by high-energy trauma. The surgical implant generation network (SIGN®) program offers two different intramedullary nails ...

Neuroaxonal Injury May Mediate the Association Between Hyperglycemia and Prognosis in Spontaneous Subarachnoid Hemorrhage 

Santana Moreno, Daniel; Llull Estrany, Laura; Mosteiro Cadaval, Alejandra; Pedrosa Eguílez, Leire; Pujol Fontrodona, Gabriel; Zattera, Luigi; Werner, Mariano; Martín, Abraham; Justicia Mercader, Carles; Chamorro, Ángel; Torné, Ramón; Amaro Delgado, Sergio (Data de publicació: 2026-04-09)

Hyperglycemia during early brain injury (EBI) period after spontaneous subarachnoid hemorrhage (SAH) is associated with poor outcome, but the underlying physiopathology is unknown. This study assessed if hyperglycemia ...

Genomic classification and outcomes of young patients with polycythemia vera and essential thrombocythemia according to the presence of splanchnic vein thrombosis and its chronology 

Garrote, Marta; López Guerra, Mónica; García Pagán, Juan Carlos; Arellano Rodrigo, Eduardo; Ferrer Marín, Francisca; Hernández Boluda, Juan Carlos; Bellosillo Paricio, Beatriz; Nomdedeu i Fàbrega, Meritxell; Hernández Gea, Virginia; Triguero, Ana; Guijarro Tomas, Francisca; Álamo Moreno, José Ramón; Baiges, Anna; Turon, Fanny; Colomer Pujol, Dolors; Cervantes Requena, F.; Alvarez Larrán, Alberto (Data de publicació: 2026-04-07)

To elucidate the role of splanchnic vein thrombosis (SVT) and genomic characteristics in prognosis and survival, we compared patients with polycythemia vera (PV) or essential thrombocythemia (ET) presenting SVT at diagnosis ...

Genome-Wide DNA Methylation in Early-Onset-Dementia Patients Brain Tissue and Lymphoblastoid Cell Lines 

Ramos Campoy, Oscar; Comas Albertí, Aina; Hervas, David; Borrego Écija, Sergi; Bosch Capdevila, Beatriz; Sandoval, Juan; Fort Aznar, Laura; Moreno Izco, Fermín; Fernández Villullas, Guadalupe; Molina Porcel, Laura; Balasa, Mircea; Lladó Plarrumaní, Albert; Sánchez del Valle Díaz, Raquel; Antonell Boixader, Anna, 1978- (Data de publicació: 2025-09-01)

Epigenetics, a potential underlying pathogenic mechanism of neurodegenerative diseases, has been in the scope of several studies performed so far. However, there is a gap in regard to analyzing different forms of early-onset ...

Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia 

Gimenez, Neus; Tripathi, Rupal; Giró, Ariadna; Rosich, Laia; López Guerra, Mónica; López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; Mas, José Manuel; Pérez Galán, Patricia; Delgado, Julio (Delgado González); Campo Güerri, Elias; Farrés, Judith; Colomer Pujol, Dolors (Data de publicació: 2025-10-23)

Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL ...

Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets 

López Oreja, Irene; Playa-Albinyana, Heribert; Arenas Ríos, Fabián; López Guerra, Mónica; Colomer Pujol, Dolors (Data de publicació: 2025-09-26)

Chronic lymphocytic leukemia (CLL) is characterized by a high degree of genetic variability and interpatient heterogeneity. In the last decade, novel alterations have been described. Some of them impact on the prognosis ...

Immunoparesis defined by heavy/light chain pair suppression in smoldering multiple myeloma shows initial isotype specificity and involves other isotypes in advanced disease 

Isola, Ignacio; Moreno Fajardo, David Fernando; Moga, Esther; Mena Jaramillo, Mari Pau; Tovar Gomis, Natalia; Rodriguez Lobato, Luis Gerardo; Oliver Caldes, Aina; Salgado Martín, María del Carmen; Brasó Maristany, Fara; Yagüe Ribes, Jordi; Cibeira López, M. Teresa; Prat Aparicio, Aleix; Rosiñol Dachs, Laura; Bladé Creixenti, Joan; Fernández de Larrea Rodríguez, Carlos (Data de publicació: 2025-09-19)

Smoldering multiple myeloma (SMM) is an asymptomatic and biologically heterogeneous plasma cell disorder, with a highly variable clinical course. Immunoparesis, defined by total immunoglobulin measurements, has been shown ...

Identification of Dhx15 as a Major Regulator of Liver Development, Regeneration, and Tumor Growth in Zebrafish and Mice 

Portolés, Irene; Ribera, Jordi; Fernández Galán, Esther; Lecue Costas, Elena; Casals Mercadal, Gregori; Melgar Lesmes, Pedro; Fernández Varo, Guillermo; Boix i Ferrero, Loreto; Sanduzzi Zamparelli, Marco; Aishwarya, Veenu; Reig, María; Jiménez Povedano, Wladimiro; Morales Ruiz, Manuel (Data de publicació: 2025-08-27)

RNA helicase DHX15 plays a significant role in vasculature development and lung metastasis in vertebrates. In addition, several studies have demonstrated the overexpression of DHX15 in the context of hepatocellular carcinoma. ...

Cognitive and motor improvement after retesting in normal-pressure hydrocephalus: a real change or merely a learning effect? 

Solana Díaz, Elisabeth; Poca Pastor, María Antonia; Sahuquillo, Juan; Benejam, Bessy; Junqué i Plaja, Carme, 1955-; Dronavalli, Mithilesh (Data de publicació: 2025-09-26)

Object The test-retest method is commonly used in the management of patients with normal-pressure hydrocephalus (NPH). One of the most widely used techniques in the diagnosis of this condition is evaluation of the patient's ...

SF3B1 mutation-mediated sensitization to H3B-8800 splicing inhibitor in chronic lymphocytic leukemia 

López Oreja, Irene; Gohr, Andre; Playa-Albinyana, Heribert; Giró, Ariadna; Arenas Ríos, Fabián; Higashi, Morihiro; Tripathi, Rupal; López Guerra, Mónica; Irimia Martínez, Manuel; Aymerich Gregorio, Marta; Valcárcel Juárez, Juan; Bonnal, Sophie; Colomer Pujol, Dolors (Data de publicació: 2025-11-12)

Splicing factor 3B subunit 1 (SF3B1) is involved in pre-mRNA branch site recognition and is the target of antitumor-splicing inhibitors. Mutations in SF3B1 are observed in 15% of patients with chronic lymphocytic leukemia ...

Exploring the Microbiome of Diabetic Foot Ulcers: A Focus on Cases with a Clinical Worse Outcome 

Soldevila-Boixader, Laura; Carrera Salinas, Anna; Mur, Isabel; Morata, Laura; Rivera, Alba; Bosch Mestres, Jordi; Montero Saez, Abelardo; Martínez Castillejo, Jéssica; Benito, Natividad; Martí Martí, Sara; Murillo Rubio, Óscar (Data de publicació: 2025-09-03)

Background/Objectives: We evaluated the diabetic foot ulcer (DFU) microbiome in clinical situations identified as risk factors for a worse outcome and explored the roles of the most abundant microorganisms. Methods: A ...

Cognitive symptoms in schizophrenia: an analysis of awareness, assessment, and management practices among psychiatrists and primary care physicians 

Agüera Ortiz, Luis; Aragonès, Enric; Buch Vicente, Bárbara; Mendive, Juan Manuel; Peña Granger, Mercedes; Vieta i Pascual, Eduard, 1963- (Data de publicació: 2025-10-22)

Introduction: Cognitive symptoms contribute to the worsening of functionality in people with schizophrenia. The objective of this study was to explore the current knowledge about cognitive symptoms (relevance, evaluation, ...

Pharmacological treatments for atypical depression: A systematic review and network meta-analysis of randomized controlled trials 

Fornaro, Michele; Caiazza, Claudio; Pistone, Luca; Di Lorenzo, Chiara; Crincoli, Walter; Pezone, Rosanna; Tufano, Giovanni; Oliva, Vincenzo; De Prisco, Michele ; Miola, Alessandro; Iasevoli, Felice; Vieta i Pascual, Eduard, 1963-; Solmi, Marco; De Bartolomeis, Andrea (Data de publicació: 2025-10-22)

Introduction: Atypical depression is a highly prevalent subtype that includes mood reactivity, hypersomnia, and leaden paralysis, necessitating different therapeutic approaches than melancholic depression. No network ...

Imaging Efficacy of [18F]CTT1057 PET/CT in Patients with Biochemically Recurrent Prostate Cancer: Results from GuidePath-A Phase 3, Prospective Multicenter Study 

Fanti, Stefano; Robles Barba, Javier Jesus; Behr, Spencer; Maurer, Tobias; Paredes Barranco, Pilar; Walz, Jochen; Duch, Joan; Simo Perdigo, Marc; Mainta, Ismini Charis; Bonnefoy, Pierre Benoit; Coulanges, Medge; Tang, Jun; Seigne, Christelle; Wilke, Celine; Catafau, Ana M.; Iagaru, Andrei; Aggarwal, Rahul (Data de publicació: 2025-09-25)

Improved diagnostic accuracy in patients with prostate cancer at first biochemical recurrence (BCR) with low prostate-specific antigen (PSA) levels is needed. This prospective study (GuidePath; NCT04838613) aimed to evaluate ...

Resting-state functional magnetic resonance imaging activity and connectivityand cognitive outcome in traumatic brain injury 

Palacios, Eva M.; Sala Llonch, Roser; Junqué i Plaja, Carme, 1955-; Roig Rovira, María Teresa; Tormos, José María; Bargalló Alabart, Núria; Vendrell i Gómez, Pere (Data de publicació: 2025-09-15)

Importance The study of brain activity and connectivity at rest provides a unique opportunity for the investigation of the brain substrates of cognitive outcome after traumatic axonal injury. This knowledge may contribute ...

Life’s Simple 7 and Risk of Peripheral Artery Disease: Results from the PREDIMED Study and an Updated Meta-Analysis 

López Laguna, Nieves; Toledo Atucha, Estefanía; Hershey, María S.; Babio, Nancy; Sorlí, José V.; Ros Rahola, Emilio; Muñoz Pérez, Miguel Ángel; Estruch Riba, Ramon; Lapetra, José; Muñoz Bravo, Carlos; Fiol Sala, Miguel; Bautista Castaño, Inmaculada; Pintó Sala, Xavier; Ortega Azorín, Carolina; Hernando Redondo, Javier; Salas Salvadó, Jordi; Tojal Sierra, Lucas; Martínez-González, Miguel Ángel, 1957-; Ruiz Canela, Miguel (Data de publicació: 2025-09-08)

Background: Peripheral artery disease (PAD) is a major vascular condition often overlooked in prevention strategies. We aimed to evaluate the association between cardiovascular health, measured by Life's Simple 7 (LS7), ...

A review of vancomycin, gentamicin and amikacin population pharmacokientic models in neonates and infants. 

Albanell Fernández, Marta; Bastida Fernández, Carla; Rodríguez Reyes, Montse; Soy Muner, Dolors (Data de publicació: 2025-11-07)

Abstract Population pharmacokinetic (popPK) models are an essential tool when implementing therapeutic drug monitoring (TDM) and to overcome dosing challenges in neonates in clinical practice. Since vancomycin, gentamicin, ...

The PADRIS-PRESTO Cohort: A Comprehensive Population-Based Study on Mental Health in Catalonia 

De Prisco, Michele; Oliva, Vincenzo; Fico, Giovanna; Mas, Ariadna; Valenzuela-Pascual, Clàudia; Montejo Egido, Laura; Bort, Marta; Sommerhof, Constanza; Bortolozzi, Analia; Miquel Rio, Lluís; Vilella, Elisabet; Forte, Maria Florencia; Fortea, Lydia; Fernández-Plaza, Tábatha; Giménez Palomo, Anna; Sagué-Vilavella, Maria; Madero Gómez, Santiago; Llorca-Bofí, Vicent; Bioque Alcázar, Miquel; Grande i Fullana, Iria; Murru, Andrea; Pacchiarotti, Isabella; Cavero Álvarez, Myriam; Blanch Andreu, Jordi; Viñas-Bardolet, Clara; Aparicio-Nogué, Vicenç; Martínez-Cerdá, Juan Francisco; Parellada Rodón, Eduard; Martínez-Arán, Anabel, 1971-; Radua, Joaquim; Vieta i Pascual, Eduard, 1963-; Hidalgo Mazzei, Diego; Anmella, Gerard (Data de publicació: 2025-11-10)

Background: Mental disorders affect nearly 970 million people worldwide, impacting individuals and healthcare systems. Large population databases offer insights often unattainable in smaller studies, but their findings may ...

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