Ara mostrant els elements 1-20 de 2975

    Mometasone and desloratadine additive effect on eosinophil survival and cytokine secretion from epithelial cells 

    Callejas, Francisco de Borja; Martínez Antón, Ma. Asunción; Mendez-Arancibia, Eva; Alobid, Isam; Pujols Tarrés, Laura; Valero, Antonio; Picado Vallés, César; Roca i Ferrer, Jordi; Mullol i Miret, Joaquim (2011-06-08)

    Although antihistamines and topical corticosteroids are used in combination to treat allergic rhinitis, their additive effect has not been yet demonstrated. The aim was investigate the antiinflammatory additive effect of ...

    Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn's disease. 

    Rimola Gibert, Jordi; Rodríguez, S.; García Bosch, Orlando; Ordás, I.; Ayala, Edgar; Aceituno, Montserrat; Pellisé Urquiza, Maria; Ayuso Colella, Carmen; Ricart, Elena; Donoso Bach, Lluís; Panés Díaz, Julià (2011-07-07)

    Assessment of disease extension and activity is crucial to guide treatment in Crohn’s disease. The objective of the current cross-sectional study was to determine the accuracy of MR for this assessment...

    Outpatient Quick Diagnosis Units for the evaluation of suspected severe diseases: an observational, descriptive study 

    Bosch Aparici, Francisco Javier; Foix, Anna; Jordan, Anna; Coca, Antonio; López-Soto, Alfonso (2012-01-18)

    Background: Hospitals in countries with public health systems have recently adopted organizational changes to improve efficiency and resource allocation, and reducing inappropriate hospitalizations has been established as ...

    Hexokinase 2, Glycogen Synthase and Phosphorylase Play a Key Role in Muscle Glycogen Supercompensation 

    Irimia, José M.; Rovira Juárez, Jordi; Nielsen, Jakob N.; Guerrero, Mario; Wojtaszewski, Jorgen F. P.; Cussó Fresquet, M. Roser (2013-05-16)

    Background: Glycogen-depleting exercise can lead to supercompensation of muscle glycogen stores, but the biochemical mechanisms of this phenomenon are still not completely understood. Methods: Using chronic low-frequency ...

    Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content 

    Rothwell, Joseph A.; Pérez-Jiménez, Jara; Neveu, Vanessa; Medina Remón, Alexander; M'Hiri, Nouha; García-Lobato, Paula; Manach, Claudine; Knox, Craig; Eisner, Roman; Wishart, David S.; Scalbert, Augustin (2014-03-05)

    Polyphenols are a major class of bioactive phytochemicals whose consumption may play a role in the prevention of a number of chronic diseases such as cardiovascular diseases, type II diabetes and cancers. Phenol-Explorer, ...

    An investigation of the resolution of inflammation (catabasis) in COPD. 

    Noguera, Aina; Gomez, Cristina; Faner, Rosa; Cosío, Borja G.; González Périz, Ana; Clària i Enrich, Joan; Carvajal, Angel; Agustí García-Navarro, Àlvar (2014-03-21)

    Background: Chronic Obstructive Pulmonary Disease (COPD) is characterized by an enhanced inflammatory response to smoking that persists despite quitting. The resolution of inflammation (catabasis) is a complex and highly ...

    Association of thymidylate synthase polymorphisms with acute pancreatitis and/or peripheral neuropathy in HIV-infected patients on Stavudine-Based Therapy 

    Domingo, Pere (Domingo Pedrol); Cabeza, María del Carmen; Torres, Ferran; Salazar, Juliana; Gutiérrez, Maria del Mar; Mateo, Maria Gracia; Martínez Chamorro, Esteban José; Domingo i Pedrol, Joan Carles; Fernández, Irene; Villarroya i Gombau, Francesc; Ribera, Esteban; Vidal Marsal, Francisco; Baiget Bastús, Montserrat (2014-10-08)

    BACKGROUND: Low expression thymidylate synthase (TS) polymorphism has been associated with increased stavudine triphosphate intracellular (d4T-TP) levels and the lipodystrophy syndrome. The use of d4T has been associated ...

    The natural hallucinogen 5-MeO-DMT, component of Ayahuasca, disrupts cortical function in rats: reversal by antipsychotic drugs 

    Riga, Maurizio S.; Soria, Guadalupe; Tudela Fernández, Raúl; Artigas Pérez, Francesc; Celada Pedrosa, Paz (2015-04-24)

    5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a natural hallucinogen component of Ayahuasca, an Amazonian beverage traditionally used for ritual, religious and healing purposes that is being increasingly used for ...

    Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis 

    Valgimigli, Marco; Sabaté Tenas, Manuel; Kaiser, Cristoph; Brugaletta, Salvatore; Torre Hernández, José María de la; Galatius, Soeren; Cequier Fillat, Àngel R.; Eberli, Franz; De Belder, Adam; Serruys, Patrick W.; Ferrante, Giuseppe (2015-06-16)

    Objectives: To examine the safety and effectiveness of cobalt-chromium everolimus eluting stents compared with bare metal stents. Design: Individual patient data meta-analysis of randomised controlled trials. Cox proportional ...

    Resumen ejecutivo del documento de consenso sobre el manejo de la patología renal en pacientes con infección por VIH 

    Górriz, José Luis; Gutiérrez, Félix; Trullás Vila, Joan Carles; Arazo, Piedad; Arribas, José Ramón; Barril, Guillermina; Cervero, Miguel; Cofán Pujol, Federico; Domingo, Pere (Domingo Pedrol); Estrada, Vicente; Fulladosa, Xavier; Galindo, María José; Gracia, Silvia; Iribarren, José A.; Knobel Freud, Hernando Javier; López-Aldeguer, José; Lozano, Fernando; Martínez Castelao, Alberto; Martínez Chamorro, Esteban José; Mazuecos, María A.; Miralles, Celia; Montañés, Rosario; Negredo, Eugènia; Palacios, Rosario; Pérez Elías, María Jesús; Portilla, Joaquín; Praga, Manuel; Quereda, Carlos; Rivero, Antonio; Santamaría, Juan M.; Sanz, José; Sanz, Jesús; Miró Meda, José M. (José María), 1956- (2015-12-10)

    El objetivo de este documento es actualizar las recomendaciones sobre la evaluación y el manejo de la afectación renal en pacientes con infección por el VIH del año 2010. La función renal debe monitorizarse en todos los ...

    ChainRank, a chain prioritisation method for contextualisation of biological networks 

    Tényi, Ákos; Atauri Carulla, Ramón de; Gomez Cabrero, David; Cano Franco, Isaac; Clarke, Kim; Falciani, Francesco; Cascante i Serratosa, Marta; Roca Torrent, Josep; Maier, Dieter (2016-01-19)

    Advances in high throughput technologies and growth of biomedical knowledge have contributed to an exponential increase in associative data. These data can be represented in the form of complex networks of biological ...

    FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies 

    Martínez Aranda, Antonio; Hernández, Vanessa; Guney, Emre; Muixí, Laia; Foj, Ruben; Baixeras, Núria; Cuadras, Daniel; Moreno Aguado, Víctor; Urruticoechea Ribate, Ander; Gil, Miguel; Oliva Miguel, Baldomero; Moreno, Ferran; González Suárez, Eva; Vidal, Noemí; Andreu, Xavier; Seguí, Miquel A.; Ballester, Rosa; Castella, Eva; Sierra Jiménez, Àngels (2016-02-09)

    Brain metastasis is a devastating problem in patients with breast, lung and melanoma tumors. GRP94 and FN14 are predictive biomarkers over-expressed in primary breast carcinomas that metastasized in brain. To further ...

    Human serum versus human serum albumin supplementation in human islet pretransplantation culture: in vitro and in vivo assessment 

    Nacher, Montserrat; Estil·les Altimiras, Elisabet; García, Ainhoa; Nadal, Belen; Pairó, Mar; García, Cristofer; Secanella, Lluís; Novials, Anna; Montanya Mias, Eduard (2016-03-22)

    There is conflicting evidence favoring both the use of human serum (HS) and of human serum albumin (HSA) in human islet culture. We evaluated the effects of HS versus HSA supplementation on 1) in vitro β-cell viability and ...

    Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation 

    Balcells, Eva; Gimeno Santos, Elena; Batlle, Jordi de; Ramon, Maria Antonia; Rodríguez, Esther; Benet, Marta; Farrero, Eva; Ferrer Monreal, Antonio; Guerra, Stefano; Ferrer, Jaume; Sauleda, Jaume; Barberà i Mir, Joan Albert; Agustí García-Navarro, Àlvar; Rodríguez-Roisin, Robert; Gea Guiral, Joaquim; Antó i Boqué, Josep Maria; García Aymerich, Judith; PAC-COPD Study Group (2016-04-11)

    Background Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD. Methods The PAC-COPD cohort included 342 COPD patients ...

    Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8) 

    Ejarque, M.; Mir-Coll, J.; Gomis, Ramon, 1946-; German, Michael S.; Lynn, Francis C.; Gasa, Rosa (2016-04-18)

    Atonal Homolog 8 (Atoh8) is a basic helix-loop-helix (bHLH) transcription factor that is highly conserved across species and expressed in multiple tissues during embryogenesis. In the developing pancreas, Atoh8 is expressed ...

    Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas 

    Pujadas i Rovira, Gemma; Cervantes, Sara; Tutusaus, Anna; Ejarque, M.; Sanchez, Lidia; García, A.; Esteban, Yaiza; Fargas, L.; Alsina, B.; Hartmann, C.; Gomis, Ramon, 1946-; Gasa, Rosa (2016-04-18)

    Transcriptional and signaling networks establish complex cross-regulatory interactions that drive cellular differentiation during development. Using microarrays we identified the gene encoding the ligand Wnt9a as a candidate ...

    The role of red blood cell exchange for severe imported malaria in the artesunate era: a retrospective cohort study in a referral centre 

    Calvo-Cano, Antonia; Gómez Junyent, Joan; Lozano Molero, Miguel; Castro, Pedro; Cid Vidal, Joan; Nicolás Arfelis, Josep Maria; Quintó, Llorenç; Martin, Maite; Muñoz, José; Gascón i Brustenga, Joaquim (2016-05-19)

    BACKGROUND: Intravenous artesunate has replaced quinine as the first-line therapy for severe imported malaria, given its anti-malarial superiority shown in clinical trials conducted in ...

    Evaluation of a Mixing versus a Cycling Strategy of Antibiotic Use in Critically-Ill Medical Patients: Impact on Acquisition of Resistant Microorganisms and Clinical Outcomes 

    Cobos-Trigueros, Nazaret; Solé, Mar; Castro, Pedro; Torres, Jorge Luis; Rinaudo, Mariano; Lazzari, Elisa de; Morata, Laura; Hernández-Munain, Cristina; Fernández, Sara (Fernández García); Soriano Viladomiu, Alex; Nicolás Arfelis, Josep Maria; Mensa Pueyo, Josep; Vila Estapé, Jordi; Martínez, José Antonio (Martínez Martínez) (2016-05-19)

    OBJECTIVE: To compare the effect of two strategies of antibiotic use (mixing vs. cycling) on the acquisition of resistant microorganisms, infections and other clinical outcomes. METHODS: ...

    The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research 

    Cano Franco, Isaac; Tényi, Ákos; Schueller, Christine; Wolff, Martin; Huertas Migueláñez, M. Mercedes; Gomez Cabrero, David; Antczak, Philipp; Roca Torrent, Josep; Cascante i Serratosa, Marta; Falciani, Francesco; Maier, Dieter (2016-05-25)

    Background Previously we generated a chronic obstructive pulmonary disease (COPD) specific knowledge base (http://www.copdknowledgebase.eu) from clinical and experimental data, text-mining results and public databases. ...

    Timing of food intake is associated with weight loss evolution in severe obese patients after bariatric surgery 

    Ruiz Lozano, Tania Pamela; Vidal i Cortada, Josep; De Hollanda, A.; Scheer, F. A. J. L.; Garaulet Aza, Marta; Izquierdo Pulido, Maria (2016-06-13)

    Background Recent research has demonstrated a relationship between the timing of food intake and weight loss in humans. However, whether the meal timing can be associated with weight loss in patients treated with bariatric ...