CSF Biomarkers in COVID-19 Associated Encephalopathy and Encephalitis Predict Long-Term Outcome 

Guasp, M.; Muñoz Sánchez, G.; Martinez Hernandez, E.; Santana, D.; Carbayo, Á.; Naranjo, L.; Bolós, U.; Framil, M.; Saiz, A.; Balasa, M.; Ruiz García, R.; Sanchez Valle, R.; Barcelona Neuro-COVID Study Group (2024-03-25)

Patients with coronavirus disease 2019 (COVID-19) frequently develop acute encephalopathy and encephalitis, but whether these complications are the result from viral-induced cytokine storm syndrome or anti-neural autoimmunity ...

Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease 

Gelpi, E.; Baiardi, S.; Nos, C.; Dellavalle, S.; Aldecoa, I.; Ruiz García, R.; Ispierto, L.; Escudero, D.; Casado, V.; Barranco, E.; Boltes, A.; Molina Porcel, L.; Bargallo, N.; Rossi, M.; Mammana, A.; Tiple, D.; Vaianella, L.; Stoegmann, E.; Simonitsch Klupp, I.; Kasprian, G.; Klotz, S.; Hoftberger, R.; Budka, H.; Kovacs, G. G.; Ferrer, I.; Capellari, S.; Sanchez Valle, R.; Parchi, P. (2024-03-25)

The methionine (M)-valine (V) polymorphic codon 129 of the prion protein gene (PRNP) plays a central role in both susceptibility and phenotypic expression of sporadic Creutzfeldt-Jakob diseases (sCJD). Experimental ...

Brain connectivity correlates of cognitive dispersion in a healthy middle-aged population: influence of subjective cognitive complaints 

Mulet Pons, Lídia; Solé Padullés, Cristina; Cabello Toscano, María; Abellaneda Pérez, Kilian; Perellón Alfonso, Rubén; Cattaneo, Gabriele; Solana Sánchez, Javier; Alviárez Schulze, Vanessa; Bargalló Alabart, Núria​; Tormos Muñoz, Josep Maria; Pascual Leone, Álvaro; Bartrés Faz, David; Vaqué Alcázar, Lídia (2024-01-24)

Cognitive dispersion, representing intraindividual fluctuations in cognitive performance, is associated with cognitive decline in advanced age. We sought to elucidate sociodemographic, neuropsychological, and brain ...

Cognitive Performance and Health-Related Quality of Life in Patients with Neuromyelitis Optica Spectrum Disorder 

López Soley, Elisabet; Meca Lallana, José E.; Llufriu Duran, Sara; Blanco, Yolanda; Gómez Ballesteros, Rocío; Maurino, Jorge; Pérez Miralles, Francisco; Forero, Lucia; Calles, Carmen; Martínez Ginés, María L.; González Suárez, Inés; Boyero, Sabas; Romero Pinel, Lucía; Sempere, Ángel P.; Meca Lallana, Virginia; Querol, Luís; Costa Frossard, Lucienne; Sepúlveda, María; Solana, Elisabeth (2024-03-05)

The frequency of cognitive impairment (CI) reported in neuromyelitis optica spectrum disorder (NMOSD) is highly variable, and its relationship with demographic and clinical characteristics is poorly understood. We aimed ...

A motivational interview program for cardiac rehabilitation after acute myocardial infarction: study protocol of a randomized controlled trial in primary healthcare 

Rodríguez Romero, R.; Falces, C.; Kostov, Benchi; García Planas, N.; Blat Guimerà, E.; Alvira Balada, M. C.; López Poyato, M.; Benito Serrano, M. L.; Vidiella Piñol, I.; Zamora Sánchez, J. J.; Benet, M.; Garnacho Castaño, M. V.; Santos Ruiz, S.; Santesmases Masana, R.; Roura Rovira, Silvia; Benavent Àreu, Jaume; Sisó Almirall, Antoni; González de Paz, Luis (2024-01-24)

Cardiac rehabilitation after acute myocardial infarction permits recovery of the heart function and enables secondary prevention programs in which changes in lifestyle habits are crucial. Cardiac rehabilitation often takes ...

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodelling of both postsynaptic density and NMDA receptor signalling 

Torres Peraza, Jesús Fernando; Giralt Torroella, Albert; García Martínez, Juan M.; Pedrosa, Edurne; Canals i Coll, Josep M.; Alberch i Vié, Jordi (2024-02-16)

We study the striatal susceptibility to NMDA receptor (NMDAR)-</p><p>mediated injury of two Huntington’s disease (HD) transgenic mice:</p><p>R6/1 and R6/1:BDNF+/−. We found that R6/1:BDNF+/− mice – which</p><p>express ...

Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in cohort of 35 infected fetuses. 

Hawkins-Villarreal, Ameth; Castillo, Karen; Nadal Serra, Alfons; Planas i Marcé, Sílvia, 1965-; Moreno Espinosa, Ana L.; Alarcón, Ana; Rebollo Polo, Mónica; Figueras Retuerta, Francesc; Gratacós Solsona, Eduard; Eixarch Roca, Elisenda; Goncé Mellgren, Anna (2024-02-05)

To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.

Cortical thickness modeling and variability in Alzheimer's disease and frontotemporal dementia. 

Pérez Millan, Agnès; Borrego Écija, Sergi; Falgàs Martínez, Neus; Juncà Parella, Jordi; Bosch Capdevila, Beatriz; Tort Merino, Adrià; Antonell, Anna; Bargalló Alabart, Núria; Rami González, Lorena; Balasa, Mircea; Lladó Plarrumaní, Albert; Sala Llonch, Roser; Sánchez Valle, Raquel (2025-03-27)

Background and objective: Alzheimer's disease (AD) and frontotemporal dementia (FTD) show different patterns of cortical thickness (CTh) loss compared with healthy controls (HC), even though there is relevant heterogeneity ...

Interlink between Inflammation and Oxidative Stress in Age-Related Macular Degeneration: Role of Complement Factor H 

Romero Vázquez, Sara; Llorens Bellés, Víctor; Soler Boronat, Alba; Figueras Roca, Marc; Adán Civera, Alfredo; Molins Monteys, Blanca (2025-03-14)

Age-related macular degeneration (AMD) heads the list of legal blindness among the elderly population in developed countries. Due to the complex nature of the retina and the variety of risk factors and mechanisms involved, ...

Optimal opportunistic screening of atrial fibrillation using pulse palpation in cardiology outpatient clinics: Who and how 

Bañeras, Jordi; Pariggiano, Ivana; Rodenas Alesina, Eduard; Oristrell, Gerard; Escalona, Roxana; Miranda, Berta; Rello, Pau; Soriano, Toni; Gordon, Blanca; Belahnech, Yassin; Calabró, Paolo; García Dorado, David; Ferreira González, Ignacio; Radua, Joaquim (2023-07-21)

Atrial fibrillation (AF) remain a prevalent undiagnosed condition frequently encountered in primary care.We aimed to find the parameters that optimize the diagnostic accuracy of pulse palpation to detect AF. We also aimed ...

Cell death in hepatocellular carcinoma: Pathogenesis and therapeutic opportunities 

Garcia Pras, E.; Fernández Iglesias, A.; Gracia Sancho, J.; Pérez del Pulgar Gallart, Sofía (2024-02-07)

Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and the third leading cause of cancer death worldwide. Closely associated with liver inflammation and fibrosis, hepatocyte cell death is a common ...

Academic Productivity of Young People With Allergic Rhinitis: A MASK-air Study 

Viera, Rafael José; Pham-Thi, Nhân; Antó, Josep M.; Czarlewski, Wienczyslawa; Sá-Sousa, Ana; Amaral, Rita; Bedbrook, Anna; Bosnic-Anticevich, Sinthia; Brussino, Luisa; Canonica, G. Walter; Cecchi, Lorenzo; Cruz, Álvaro A.; Fokkens, Wytske J.; Gemicioglu, Bilun; Haahtela, Tali; Ivancevich, Juan Carlos; Klimek, Ludger; Kuna, Piotr; Kvedariene, Violeta; Larenas Linnemann, Désirée; Morais-Almeida, Mario; Mullol, Joaquim; Niedoszytko, Marek; Okamoto, Yoshitaka; Papadopoulos, Nikolaos G.; Patella, Vincenzo; Pfaar, Oliver; Regateiro, Frederico S.; Reitsma, Sietze; Rouadi, Philip W.; Samolinski, Boleslaw; Sheikh, Aziz; Taborda Barata, Luis; Toppila-Salmi, Sanna; Sastre, Joaquín; Tsiligianni, Ioanna; Valiulis, Arunas; Ventura, María Teresa; Waserman, Susan; Yorgancioglu, Arzu; MASK Study Group; Sousa Pinto, Bernardo; Zidarn, Mihaela; Zuberbier, Torsten; Fonseca, João A.; Bousquet, Jean (2024-03-25)

BACKGROUND: Several studies have suggested an impact of allergic rhinitis on academic productivity. However, large studies with real-world data (RWD) are not available. OBJECTIVE: To use RWD to assess the impact of allergic ...

Exercise Capacity in Children and Adolescents With Congenital Heart Disease: A Systematic Review and Meta-Analysis 

Villaseca Rojas, Yenny; Varela Melo, Javiera; Torres Castro, Rodrigo; Mazzucco, Guillermo; Vilaró, Jordi; Blanco Vich, Isabel; Vasconcello Castillo, Luis (2023-07-26)

Congenital heart disease (CHD) entails structural defects in the morphogenesis of the heart or its main vessels. Analyzing exercise capacity of children and adolescents with CHD is important to improve their functional ...

Heart failure during the COVID-19 pandemic: clinical, diagnostic, management, and organizational dilemmas 

Palazzuoli, Alberto; Metra, Marco; Collins, Sean P.; Adamo, Marianna; Ambrosy, Andrew P.; Antohi, Laura E.; Ben Gal, Tuvia; Farmakis, Dimitrios; Gustafsson, Finn; Hill, Loreena; Lopatin, Yuri; Tramonte, Francesco; Lyon, Alexander; Masip, Josep (Masip i Utset); Miró i Andreu, Òscar; Moura, Brenda; Mullens, Wilfried; Radu, Razvan I.; Abdelhamid, Magdy; Anker, Stefan; Chioncel, Ovidiu (2023-06-26)

The coronavirus 2019 (COVID-19) infection pandemic has affected the care of patients with heart failure (HF). Several consensus documents describe the appropriate diagnostic algorithm and treatment approach for patients ...

Physiological lentiviral vectors for the generation of improved CAR-T cells 

Tristán Manzano, María; Maldonado Pérez, Noelia; Justicia Lirio, Pedro; Muñoz, Pilar; Cortijo Gutiérrez, Marina; Pavlovic, Kristina; Jiménez Moreno, Rosario; Nogueras, Sonia; Carmona, M. Dolores; Sánchez Hernández, Sabina; Aguilar Gonzalez, Araceli; Castellà Castellà, Maria; Juan, Manel; Marañón, Concepción; Marchal, Juan Antonio; Benabdellah, Karim; Herrera, Concha; Martín, Francisco (2023-07-26)

Anti-CD19 chimeric antigen receptor (CAR)-T cells have achieved impressive outcomes for the treatment of relapsed and refractory B-lineage neoplasms. However, important limitations still remain due to severe adverse events ...

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients 

Restrepo, Marcos I.; Babu, Bettina L.; Reyes, Luis F.; Chalmers, James D.; Soni, Nilam J.; Sibila Vidal, Oriol; Faverio, Paola; Cillóniz, Catia; Rodriguez-Cintron, William; Aliberti, Stefano; GLIMP Study Group (2019-07-09)

Pseudomonas aeruginosa is a challenging bacterium to treat due to its intrinsic antibiotic resistance to the most frequently used antibiotics in patients with community-acquired pneumonia (CAP). Data about the global burden ...

Paraneoplastic cerebellar ataxia and antibodies to metabotropic glutamate receptor 2 

Ruiz García, Raquel; Martinez Hernandez, Eugenia; Joubert, Bastien; Petit Pedrol, Mar; Pajarón Boix, Elena; Fernández, Verónica; Salais, Lidia; Pozo, María del; Armangué, Thaís; Sabater Baudet, Lidia; Dalmau Obrador, Josep; Graus, Francesc (2022-03-09)

To report the presence of a new neuronal surface antibody against the metabotropic glutamate receptor 2 antibody (mGluR2-Ab) in 2 patients with paraneoplastic cerebellar ataxia.mGluR2-Abs were initially characterized by ...

Resistance mechanisms and molecular epidemiology of Pseudomonas aeruginosa strains from patients with bronchiectasis 

Cabrera Ortega, Roberto; Fernández Barat, Laia; Vázquez, Nil; Alcaraz-Serrano V; Bueno Freire, Leticia; Amaro, Rosanel; López Aladid, Rubén; Oscanoa, Patricia; Muñoz López, Laura; Vila Estapé, Jordi; Torres Martí, Antoni (2022-04-01)

Non-cystic fibrosis bronchiectasis (BE) is a chronic structural lung condition that facilitates chronic colonization by different microorganisms and courses with recurrent respiratory infections and frequent exacerbations. ...

Unilateral axilo-breast approach (UABA) with gas insufflation versus open conventional hemithyroidectomy: A prospective comparative study 

Saavedra Pérez, David; Manyalich, Martí; Domínguez, Paula; Farguell, Jordi; Rull, Ramon; López Boado, Miguel A.; Vilaça, Jaime; Vidal Pérez, Oscar (2024-02-26)

Background: The objective of this study was to compare with the conventional open approach, the surgical and aesthetic results of endoscopic thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation ...

Functional Evidence of <i>CCDC186</i> as a New Disease-Associated Gene with Endocrine and Central Nervous System Alterations 

Arrabal, L.; Muñoz Pujol, G.; Medina Martínez, I.; Gort, L.; García Villoria, Judit; Roldán, S.; Tort, Frederic; Ribes Rubió, Maria Antònia (2024-02-19)