Universitat de Barcelona
Els materials de recerca de la Universitat de Barcelona (UB) a RECERCAT s'obtenen de les col·leccions de Recerca del Dipòsit Digital de la UB.
Si sou membre de la UB i esteu interessat a publicar materials de recerca contacteu amb
dipositdigital@ub.edu
o consulteu les
indicacions
.
Política d’accés obert a la UB
Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.
Hyperglycemia during early brain injury (EBI) period after spontaneous subarachnoid hemorrhage (SAH) is associated with poor outcome, but the underlying physiopathology is unknown. This study assessed if hyperglycemia ...
Heavy and daily use of cannabis with high contents of Delta 9-tetrahydrocannabinol (THC) during adolescence is associated with an increased risk of developing psychotic disorders later in life. Here, we treated mice with ...
Background: Mental disorders affect nearly 970 million people worldwide, impacting individuals and healthcare systems. Large population databases offer insights often unattainable in smaller studies, but their findings may ...
Lafora disease (LD), the most devastating adolescence‐onset epilepsy, is caused by mutations in the EPM2A or EPM2B genes, which encode the proteins laforin and malin, respectively. Loss of function of one of these proteins, ...
Background: Most atypical depression (AD) cases endorse prominent mood reactivity, anxiety, and interpersonal sensitivity, resembling some of the characteristics of emotional dysregulation (ED). The present study assesses ...
Background and Objectives To demonstrate that an analog (SGE-301) of a brain-derived cholesterol metabolite, 24(S)- hydroxycholesterol, which is a selective positive allosteric modulator (PAM) of NMDA re- ceptors (NMDARs), ...
It has been shown that Bayesian reasoning is afected by the believability of the data, but it is unknown which conditions could potentiate or reduce such belief efect. Here, we tested the hypothesis that the belief efect ...
Background: Impairment of social cognition is documented in bipolar disorder (BD) and schizophrenia/schizoaffective disorder (SCH). In healthy individuals, women perform better than men in some of its sub-domains. However, ...
Aims Characterising the association between childhood maltreatment (CM) and cognitive functioning in bipolar disorder (BD) is crucial for improving the understanding of how early environmental risk factors impact the ...
Alterations in cortical thickness have been identified in major depressive disorder (MDD), but findings have been variable and inconsistent. To date, no reliable tools have been available for the meta-analysis of surface-based ...
Disease-modifying treatments are currently being trialled in multiple system atrophy. Approaches based solely on clinical measures are challenged by heterogeneity of phenotype and pathogenic complexity. Neurofilament light ...
Schizophrenia (SZ) is a severe mental health condition involving gene-environment interactions, with obstetric complications (OCs) conferring an elevated risk for the disease. Current research suggests that OCs may exacerbate ...
Background Cognitive behavioural therapy (CBT) is aimed to counteract cognitions and behaviours that are considered as dysfunctional. The aim of the study is to test whether the inclusion of a non-counteractive approach ...
Huntington's disease (HD) research is entering an exciting phase, with new approaches such as huntingtin lowering strategies and cell therapies on the horizon. Technological advances to direct the differentiation of stem ...
Background and objective: Brain atrophy and cognitive impairment in neurodegenerative diseases are influenced by sex. We aimed to investigate sex differences in brain atrophy and cognition in de novo Parkinson's disease ...
Emerging evidence suggests that retinal structural alterations are present in schizophrenia spectrum disorders (SSD), potentially reflecting broader neurodevelopmental and neurodegenerative processes. This cross-sectional ...
Niemann-Pick type C (NPC) disease is a childhood autosomal recessive inherited rare neurodegenerative disease characterized by accumulation of cholesterol and glycosphingolipids and where the autophagy-lysosome system and ...
Objective: Metabolic syndrome is a health-threatening condition suffered by approximately one third of schizophrenia patients and largely attributed to antipsychotic medication. Previous evidence reports a common genetic ...
Background: Continued dietary treatment since early diagnosis through newborn screening programs usually prevents brain-related complications in phenylketonuria (PKU). However, subtle neurocognitive and brain alterations ...
Introduction/Purpose: The assessment of the patients' motivation as a predictor of behavioral change via five stages (pre- contemplation, contemplation, preparation, action, and maintenance) and four processes (emotional ...
