Patologia i Terapèutica Experimental: Enviaments recents
Ara mostrant els elements 41-60 de 1064
On the role of G protein-coupled receptors oligomerization
The existence of a supramolecular organization of the G protein-coupled receptor (GPCR) is now being widely accepted by the scientific community. Indeed, GPCR oligomers may enhance the diversity and performance by which ...
Large scale purification of presynaptic plasma membranes from Torpedo marmorata electric organ
The presynaptic plasma membrane (PSPM) of cholinergic nerve terminals was purified from Torpedo electric organ using a large-scale procedure. Up to 500 g of frozen electric organ were fractioned in a single run, leading ...
Prevalence of chronic pain syndrome in patients who have undergone hallux valgus percutaneous surgery: a comparison of sciatic-femoral and ankle regional ultrasound-guided nerve blocks
Background: Chronic pain syndrome (CPS) is a common complication after operative procedures, and only a few studies have focused on the evaluation of CPS in foot-forefoot surgery and specifcally on HV percutaneous correc‑ ...
Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis
Otx1 belongs to the paired class of homeobox genes and plays a pivotal role in brain development. Here, we show that Otx1 is expressed in hematopoietic pluripotent and erythroid progenitor cells. Moreover, bone marrow cells ...
Guided tissue regeneration in severe periodontal defects in anterior teeth: case reports
Four consecutive chronic, severe periodontal bone defects in anterior teeth were treated by guided tissue regeneration, using a polytetrafluoroethylene periodontal membrane. The root surface was not specifically conditioned, ...
On the existence and function of galanin receptor heteromers in the central nervous system
Galanin receptor (GalR) subtypes 1-3 linked to central galanin neurons may form heteromers with each other and other types of G protein-coupled receptors in the central nervous system (CNS). These heteromers may be one ...
Microvascularización de los tumores cerebrales y factor angiogénico en el líquido cefalorraquídeo tumoral
Utilizando el método de tinción de la bencidina se realizó un estudio sobre las características morfológicas de la microvascularización de los tumores cerebrales; paralelamente, en la membrana corioalantoidea de embriones ...
Assessing self-reported adherence to HIV therapy by questionnaire: the SERAD (Self-Reported Adherence) study
The relationship between adherence to highly active antiretroviral therapy (HAART) and RNA-HIV viral load outcomes has been extensively shown. Although there are different procedures for assessing treatment adherence, there ...
Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse
The reelin gene encodes an extracellular protein that is crucial for neuronal migration in laminated brain regions. To gain insights into the functions of Reelin, we performed high-resolution in situ hybridization analyses ...
Actualización en el tratamiento farmacológico de la artrosis
En la Conferencia de la OARS (Osteoarthritis Research Society, 1996) los medicamentos utilizados en el tratamiento de la artrosis se clasificaron según su mecanismo de acción en fármacos de acción sintomática y/o acción ...
Percutaneous, intra-articular, chevron osteotomy (PeICO) for the treatment of mild-to-moderate hallux valgus: a case series
Purpose: Treatment for hallux valgus (HV) remains challenging. Third-generation percutaneous procedures try to reproduce chevron-type osteotomies to replicate their benefits, such as intrinsic stability and reproducibility. ...
The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling
Syntaxin 1 and synaptosome-associated protein of 25 kD (SNAP-25) are neuronal plasmalemma proteins that appear to be essential for exocytosis of synaptic vesicles (SVs). Both proteins form a complex with synaptobrevin, an ...
Fluoromodule-based reporter/probes designed for in vivo fluorescence imaging
Optical imaging of whole, living animals has proven to be a powerful tool in multiple areas of preclinical research and has allowed noninvasive monitoring of immune responses, tumor and pathogen growth, and treatment ...
Reelin regulates the development and synaptogenesis of the layer-specific entorhino-hippocampal connections
Here we examine the role of Reelin, an extracellular protein involved in neuronal migration, in the formation of hippocampal connections. Both at prenatal and postnatal stages, the general laminar and topographic distribution ...
TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections
Recent studies have suggested a role for neurotrophins in the growth and refinement of neural connections, in dendritic growth, and in activity-dependent adult plasticity. To unravel the role of endogenous neurotrophins ...
Evolution of cervical cytologic changes among HIV-infected women with normal cytology in the HAART era.
The influence of HAART on the evolution to cervical squamous intraepithelial lesions (SIL) among HIV(+) women with a normal cytological test in the HAART era was studied. A retrospective cohort study (1997-2005) of ...
Dysregulated autophagy in endometriosis: molecular mechanisms, controversies, and clinical implications
Endometriosis is one of the most common gynecological diseases in women and is still one of the most understudied diseases, affecting the daily lives of patients. Although the exact cause of this condition remains unclear, ...
Redefining anterior ankle arthroscopic anatomy: medial and lateral ankle collateral ligaments are visible through dorsiflexion and non-distraction anterior ankle arthroscopy
Purpose: A thorough understanding of the arthroscopic anatomy is important to recognise pathological conditions. Although some ankle ligaments have been described as intra-articular structures, no studies have assessed the ...
Incorporació de metodologies d'e-learning per a l'aprenentatge de la farmacologia
Podeu consultar la Vuitena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/66524
A four-group urine risk classifier for predicting outcome in prostate cancer patients
Objectives: to develop a risk classifier using urine-derived extracellular vesicle RNA (UEV-RNA) capable of providing diagnostic information of disease status prior to biopsy, and prognostic information for men on active ...
