Patologia i Terapèutica Experimental

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Política d’accés obert a la UB


Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.

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Llista ítems afegits recenment

Reliability and Agreement of a Dual-Method RadiographicStandard vs. Clinical Goniometry for Shank–ForefootAlignment A GRRAS-Compliant Study 

Carrelero Camp, Sergi; Dalmau-Pastor, Miki; Oliva Garballo, Vanessa; Simon de Blas, Clara; Vergés Salas, Carles; Planell i Mas, Elena de (Fecha de publicación: 2026-04-07)

Introduction: Forefoot varus prevalence varies widely (8.6–83.67%) and may be attributableto the lack of a gold standard. Clinical methods are limited by subjective positioning andlandmark variability. This study established ...

Obtaining Muramic Acid from Staphylococcus aureus: A Simple Strategy for Axenic Isolation of Tannerella forsythia 

Pereira-Riveros, Tanya; Aguilera, Felipe; Sierra Ortigosa, Josep Maria; Berbel, Dàmaris; Vinuesa Aumedes, Teresa (Fecha de publicación: 2026-04-07)

Background: The periodontal pathogen Tannerella forsythia is auxotrophic for muramic acid (MurNAc), a key component of bacterial peptidoglycan, and dependent on an external supply of MurNAc to maintain pure laboratory ...

Photoswitching endogenous glutamate receptors in neural ensembles and single synapses in vivo 

Garrido Charles, Aida; Bosch Pita, Miquel; Lee, Hyojung; Rovira, Xavier; Pittolo, Silvia; Llobet Berenguer, Artur, 1972-; Wong, Hovy Ho-Wai; Trapero, Ana; Matera, Carlo; Papotto, Claudio; Serra, Carme; Llebaria Soldevila, Amadeu; Soriano García, Eduardo; Sánchez-Vives, María Victoria; Holt, Christine E.; Gorostiza Langa, Pablo Ignacio (Fecha de publicación: 2025-10-21)

Purpose: To interrogate animal physiology in vivo, there is a lack of non-genetic methods to control the activity of endogenous proteins with pharmacological and spatiotemporal precision. To address this need, we recently ...

CRISPR-engineered human GATA2 deficiency model uncovers mitotic dysfunction and premature aging in HSPCs, impairing hematopoietic fitness 

Romero Moya, Damià; Torralba-Sales, Eric; Calvo, Cristina; Marin-Bejar, Oskar; Magallon-Mosella, Maria; Distefano, Maximiliano; Pera, Joan; Castaño, Julio; De Giorgio, Francesca; González, Jessica; Iglesias, Arnau; Berenguer Balaguer, Clara; Schilling, Marcel; Plass, Mireya; Pasquali, Lorenzo; Català, Albert; Molina, Òscar; Wlodarski, Marcin W.; Bigas Salvans, Anna; Giorgetti, Alessandra (Fecha de publicación: 2025-10-16)

GATA2 deficiency is a monogenic transcriptopathy disorder characterized by bone marrow failure (BMF), immunodeficiency, and a high risk of developing myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). Although ...

Intraoperative brain mapping in multilingual patients: what do we know and where are we going? 

Martín Fernández, Jesús; Gabarrós, Andreu; Fernández Coello, Alejandro (Fecha de publicación: 2025-11-07)

In this review, we evaluate the knowledge gained so far about the neural bases of multilingual language processing obtained mainly through imaging and electrical stimulation mapping (ESM). We attempt to answer some key ...

Altered resting-state functional connectivity in individuals at risk for Alzheimer’s disease: a longitudinal study 

Chavarría-Elizondo, Pamela; Maturana Quijada, Pablo Andrés; Martínez Zalacaín, Ignacio; Cerro San Ildefonso, Inés del; Juaneda Seguí, Asier; Guinea Izquierdo, Andrés; Gascón-Bayarri, Jordi; Reñé Ramírez, Ramon; Urretavizcaya Sarachaga, Mikel; Ferrer, Isidro (Ferrer Abizanda); Menchón Magriñá, José Manuel; Soria, Virginia; Soriano Mas, Carles (Fecha de publicación: 2025-07-15)

Background: Resting-state functional connectivity magnetic resonance imaging (rs-fMRI) is a sensitive tool for detecting early brain changes associated with Alzheimer's disease, even in its preclinical stages. Amnestic ...

Long-lasting behavioral, molecular and functional connectivity alterations after chronic THC exposure during adolescence in mice 

Gómez Acero, Laura; Varriano, Federico; Sánchez Fernández, Nuria; Ciruela Alférez, Francisco; Soria, Guadalupe; Aso Pérez, Ester (Fecha de publicación: 2025-07-18)

Heavy and daily use of cannabis with high contents of Delta 9-tetrahydrocannabinol (THC) during adolescence is associated with an increased risk of developing psychotic disorders later in life. Here, we treated mice with ...

Circulating endothelial progenitor cell colony-forming capacity in healthy subjects: how does an endothelial colony look like? 

Ciulla, Michel M.; Giorgetti, Alessandra; Giordano, Rosaria; Silvestris, Ilaria; Cortiana, Michela; Paliotti, Roberta; Lazzari, Lorenza (Fecha de publicación: 2022-06-02)

We read with great interest the recent report in the American Journal of Cardiology by Hoetzer et al.1 The investigators addressed the question of whether in healthy, middle-aged subjects circulating endothelial progenitor ...

Variations in the course and diameter of the suprascapular nerve: Anatomical study 

Montané Blanchart, Marta; Miguel Pérez, Ma. Isabel; Rodero De Lamo, Lourdes; Möller, Ingrid; Pérez Bellmunt, Albert; Martinoli, Carlo (Fecha de publicación: 2024-01-30)

Suprascapular neuropathy is an important factor contributing to shoulder pain. Given the prevalence of nerve injury and nerve block in the suprascapular notch region, as well as the frequency of arthroscopic procedures on ...

Compartir ideas. La Universidad va al Instituto: un proyecto de aprendizaje- servicio transversal de la Universidad de Barcelona 

Amat, Concepció; Anderson, Miriam; Arias Sampériz, Bárbara; Asensio, José Antonio, 1957-; Ballesteros Pérez, Esperanza; Boix, Emili, 1956-; Bondia, David; Buenaventura Rubio, Maria Antonia; Bueno i Torrens, David, 1965-; Carrera i Sabaté, Josefina; Cases Rodrigo, Irene; Coll, Tónia, 1965-; Collado Sevilla, Antonia; Condom Bosch, Josep Lluís; Cortès Izquierdo, Ferran; Costa Cuberta, Mercè; Cuffí i Chéliz, Maria Laura; Delás, Jordi; Domingo, Josep M. (Domingo Clua); Escobedo, Anna; Escofet Roig, Anna; Esparza Pagès, Mireia; Esteban i Torné, Maria Esther; Fatjó-Vilas Mestre, Mar; Fernández Cuevas, Ana Belén; Fontiveros Sánchez, Manuel; García García, Ascensión; Giménez Merino, Antonio; Goula, Marta; Grasso, Guillermo; Grau, Eulàlia (Grau i Costa); Illán Villanueva, Montserrat; Lama López, María Xesús; Lecuona Ramírez, Itziar de; López, Marta; Madrid, Antonio, 1968-; March Pujol, Marian; Martín García, Ma. Jesús; Martínez Martín, Miquel; Massip i Bonet, M. Àngels, 1957- (Fecha de publicación: 2021-06-03)

Compartir ideas. La universidad va al instituto es un proyecto de aprendizaje servicio transversal de la Universidad de Barcelona. Este representa una propuesta de aprendizaje servicio que bajo una estructura común permite ...

Liberación de noradrenalina por reserpina I. Interacción con anfetamina y con bretilio en bazo de gato 

Planas Domingo, M. E. (Maria Eulàlia), 1945-2014; Sánchez González, S.; García-Valdecasas, Francisco, 1910-2005 (Fecha de publicación: 2017-05-25)

Continuando con experiencias anteriores ya presentadas en esta Asociación (PLANAS y cols., 1977) sobre la interacción de la reserpina con distintos fármacos, hemos estudiado en esta ocasión las posibles modificaciones del ...

Docencia sobre metodología y ética de la investigación con fármacos basada en el análisis de un incidente crítico 

Arnau, J.M.; Vallano Ferraz, Antonio; Ciruela Alférez, Francisco; Sánchez González, S.; Cuffí i Chéliz, Maria Laura; Carbonell Bardera, Lourdes; Fernández Dueñas, Víctor; Fernández, Alex (Fernández Solanas); Planas Domingo, M. E. (Maria Eulàlia), 1945-2014 (Fecha de publicación: 2022-04-12)

El objetivo docente en un seminario de la asignatura de 'Farmacología' de la licenciatura de Medicina es que los estudiantes desarrollen competencias de comprensión, análisis y evaluación crítica de los aspectos metodológicos ...

Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior 

Gomez, Juan L.; Bonaventura, Jordi; Keighron, Jacqueline; Wright, Kelsey M.; Marable, Dondre L.; Rodriguez, Lionel A.; Lam, Sherry; Carlton, Meghan L.; Ellis, Randall J.; Jordan, Chloe J.; Bi, Guo-hua; Solis, Oscar; Pignatelli, Marco; Bannon, Michael J.; Xi, Zheng-Xiong; Tanda, Gianluigi; Michaelides, Michael (Fecha de publicación: 2022-09-23)

Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown. We found that Zn2+ ...

Studies with the Golgi method in central gangliogliomas and dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease) 

Ferrer, Isidro (Ferrer Abizanda); Martí, E.; Guionnet, N.; Bella, R.; Serrano Piñol, M. Teresa; Towse, J.; Conesa Bertrán, Gerardo; Isamat de la Riva, F. (Fabián) (Fecha de publicación: 2017-07-07)

The rapid Golgi method, combined with current optical and electronmicroscopica1 techniques, was used in three central gangliogliomas and in one dysplastic gangliocytoma of the cerebellum to study the morphology of ganglionic ...

Biofunctionalization with a TGF -1 inhibitor peptide in the osseointegration of synthetic bone grafts: an in vivo study in Beagle dogs 

Cirera, Andrea; Manzanares Céspedes, María Cristina; Sevilla, Pablo; Ortiz Hernández, Mónica; Galindo Moreno, Pablo; Gil, Javier (Fecha de publicación: 2022-05-16)

Objectives: The aim of this research was to determine the osseointegration of two presentations of biphasic calcium phosphate (BCP) biomaterial¿one untreated and another submitted to biofunctionalization with a TGF- 1 ...

An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model 

Korrodi-Gregório, Luís; Lopes, Ana Margarida; Esteves, Sara L. C.; Afonso, Sandra; Lemos de Matos, Ana; Lissovsky, Andrey A.; Cruz e Silva, Odete A. B. da; Cruz e Silva, Edgar F. da; Esteves, Pedro José; Fardilha, Margarida (Fecha de publicación: 2017-03-17)

T-complex testis expressed protein 1 domain containing 4 (TCTEX1D4) contains the canonical phosphoprotein phosphatase 1 (PPP1) binding motif, composed by the amino acid sequence RVSF. We identified and validated the binding ...

Adquisició d'habilitats per investigació 

Cuffí i Chéliz, Maria Laura; Fernández Dueñas, Víctor; Fernández, Alex (Fernández Solanas); Sánchez González, S.; Ciruela Alférez, Francisco; Vallano Ferraz, Antonio; Arnau de Bolós, Josep M.; Carbonell Bardera, Lourdes (Fecha de publicación: 2014-03-13)

Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352

Cleavage of members of the synaptobrevin family by botulinum neurotoxin type D Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin 

Yamasaki, Shiqji; Binz, Thomas; Baumeister, Anja; Blasi Cabús, Joan; Link, Egenhard; Cornille, Fabrice; Roques, Bernard; Südhof, Thomas C.; Jahn, Reinhard; Niemann, Heiner; Fykse, Else Marie (Fecha de publicación: 2021-05-10)

Tetanus toxin (TeTx) and the various forms of botulinal neurotoxins (BoNT/A to BoNT/G) potently inhibit neurotransmission by means of their L chains which selectively proteolyze synaptic proteins such as synaptobrevin ...

Nanostructured Zn-substituted monetite based material induces higher bone regeneration than anorganic bovine bone and β-Tricalcium phosphate in vertical augmentation model in rabbit calvaria 

Benito-Garzón, Lorena; Guadilla, Yasmina; Díaz-Güemes, Idoia; Valdivia Gandur, Ivan; Manzanares Céspedes, María Cristina; García de Castro, Arcadio; Padilla, Sussette (Fecha de publicación: 2022-03-09)

The capacity of a nanostructured multicomponent material composed of Zn-substituted monetite, amorphous calcium phosphate, hydroxyapatite and silica gel (MSi) to promote vertical bone augmentation was compared with anorganic ...

TGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapy 

Korrodi-Gregório, Luís; Vieira Silva, Joana; Santos-Sousa, Luís; Freitas, Maria João; Felgueiras, Juliana; Fardilha, Margarida (Fecha de publicación: 2017-03-14)

Protein phosphorylation is a key mechanism by which normal and cancer cells regulate their main transduction pathways. Protein kinases and phosphatases are precisely orchestrated to achieve the (de)phosphorylation of ...

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