Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation 

Haydar, Sara; Grigorescu, Florin; Vintila, Madalina; Cogne, Yannick; Lautier, Corinne; Tutuncu, Yildiz; Brun, Jean Frederic; Robine, Jean Marie; Pugeat, Michel; Normand, Christophe; Poucheret, Patrick; Gheorghiu, Monica; Georgescu, Carmen; Badiu, Corin; Băculescu, Nicoleta; Renard, Eric; Ylli, Dorina; Badiou, Stephanie; Sutra, Thibault; Cristol, Jean Paul; Mercier, Jacques; Gomis, Ramon; Macias Solé, Josep Maria; Litvinov, Serghey; Khusnutdinova, Elza; Poiana, Catalina; Pasquali, Renato; Lauro, Davide; Sesti, Giorgio; Prudente, Sabrina; Trischitta, Vincenzo; Tsatsoulis, Agathocles; Abdelhak, Sonia; Barakat, Abdelhamid; Zenati, Akila; Ylli, Agron; Satman, Ilhan; Kanninen, Timo; Rinato, Yves; Missoni, Sasa (2019-03-26)

Branched chain amino acids (BCAA) are essential elements of the human diet, which display increased plasma levels in obesity and regained particular interest as potential biomarkers for development of diabetes. To define ...