Universitat de Barcelona
Discarded human donor organs have been shown to provide decellularized extracellular matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell sources to satisfy the need of multiple cells types in order to fully repopulate human organ-derived dECM scaffolds has opened new venues for the use of human pluripotent stem cells (hPSCs) for recellularization. In addition, three-dimensional (3D) bioprinting techniques are advancing towards the fabrication of biomimetic cell-laden biomaterial constructs. Here, we review recent progress in decellularization/recellularization and 3D bioprinting technologies, aiming to fabricate autologous tissue grafts and organs with an impact in regenerative medicine.
English
Enginyeria de teixits; Medicina regenerativa; Bioenginyeria; Tissue engineering; Regenerative medicine; Bioengineering
Elsevier
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.mattod.2016.12.005
Reproducció del document publicat a: https://doi.org/10.1016/j.mattod.2016.12.005
Materials Today, 2017, vol. 20, num. 4, p. 166-178
https://doi.org/10.1016/j.mattod.2016.12.005
info:eu-repo/grantAgreement/EC/H2020/640525/EU//REGMAMKID
cc by-nc-nd (c) Garreta, et al., 2017
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
