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dc.contributor.author | Cillóniz, Catia |
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dc.contributor.author | Dominedò, Cristina |
dc.contributor.author | Ielpo, Antonella |
dc.contributor.author | Ferrer Monreal, Miquel |
dc.contributor.author | Gabarrús, Albert |
dc.contributor.author | Battaglini, Denise |
dc.contributor.author | Bermejo Martín, Jesús |
dc.contributor.author | Meli, Andrea |
dc.contributor.author | Garcia Vidal, Carolina |
dc.contributor.author | Liapikou, Adamantia |
dc.contributor.author | Singer, Mervyn |
dc.contributor.author | Torres Martí, Antoni |
dc.date | 2019-11-25T12:17:21Z |
dc.date | 2019-11-25T12:17:21Z |
dc.date | 2019-07-02 |
dc.date | 2019-10-31T16:51:29Z |
dc.identifier | 2077-0383 |
dc.identifier | 698278 |
dc.identifier | 5752303 |
dc.identifier | 31269766 |
dc.identifier.uri | http://hdl.handle.net/2445/145319 |
dc.description | Little is known about risk and prognostic factors in very old patients developing sepsis secondary to community-acquired pneumonia (CAP). Methods: We conducted a retrospective observational study of data prospectively collected at the Hospital Clinic of Barcelona over a 13-year period. Consecutive patients hospitalized with CAP were included if they were very old (≥80 years) and divided into those with and without sepsis for comparison. Sepsis was diagnosed based on the Sepsis-3 criteria. The main clinical outcome was 30-day mortality. Results: Among the 4219 patients hospitalized with CAP during the study period, 1238 (29%) were very old. The prevalence of sepsis in this age group was 71%. Male sex, chronic renal disease, and diabetes mellitus were independent risk factors for sepsis, while antibiotic therapy before admission was independently associated with a lower risk of sepsis. Thirty-day and intensive care unit (ICU) mortality did not differ between patients with and without sepsis. In CAP-sepsis group, chronic renal disease and neurological disease were independent risk factors for 30-day mortality. Conclusion: In very old patients hospitalized with CAP, in-hospital and 1-year mortality rates were increased if they developed sepsis. Antibiotic therapy before hospital admission was associated with a lower risk of sepsis. |
dc.format | 12 p. |
dc.format | application/pdf |
dc.language | eng |
dc.publisher | MDPI |
dc.relation | Reproducció del document publicat a: https://doi.org/10.3390/jcm8070961 |
dc.relation | Journal of Clinical Medicine, 2019, vol. 8, num. 7 |
dc.relation | https://doi.org/10.3390/jcm8070961 |
dc.rights | cc by (c) Cillóniz et al., 2019 |
dc.rights | http://creativecommons.org/licenses/by/3.0/es/ |
dc.rights | info:eu-repo/semantics/openAccess |
dc.subject | Pneumònia adquirida a la comunitat |
dc.subject | Septicèmia |
dc.subject | Persones grans |
dc.subject | Community-acquired pneumonia |
dc.subject | Septicemia |
dc.subject | Older people |
dc.title | Risk and Prognostic Factors in Very Old Patients with Sepsis Secondary to Community-Acquired Pneumonia |
dc.type | info:eu-repo/semantics/article |
dc.type | info:eu-repo/semantics/publishedVersion |