Bioquímica i Biomedicina Molecular: Enviaments recents
Ara mostrant els elements 41-60 de 919
Els estudiants estrangers volen venir a Barcelona
La valoració global de Barcelona que fan en el document és que les universitats de renom de la nostra ciutat estan a disposició dels estudiants internacionals a un cost molt més baix que les universitats dels Estats Units ...
Intravitreal docosahexaenoic acid in a rabbit model: preclinical safety assessment
Purpose The purpose of the present study was to evaluate the retinal toxicity of a single dose of intravitreal docosahexaenoic acid (DHA) in rabbit eyes over a short-term period. Methods Sixteen New Zealand albino rabbits ...
From Inflammation to the Onset of Fibrosis through A2A Receptors in Kidneys from Deceased Donors.
Pretransplant graft inflammation could be involved in the worse prognosis of deceased donor (DD) kidney transplants. A2A adenosine receptor (A2AR) can stimulate anti-inflammatory M2 macrophages, leading to fibrosis if ...
La força de la indústria
He defensat reiteradament que per poder transformar el país i fer-lo competitiu, Catalunya ha d'optar per l'economia del coneixement. Això no és només produir amb menys cost, que ho és, és produir coses amb noves ...
Coffee polyphenols change the expression of STAT5b and ATF-2 modifying cyclin D1 levels in cancer cells
Background: Epidemiological studies suggest that coffee consumption reduces the risk of cancer, but the molecular mechanisms of its chemopreventive effects remain unknown. Objective: To identify differentially expressed ...
Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation
Muscle-type carnitine palmitoyltransferase 1 (CPT1β) is considered to be the gene that controls fatty acid mitochondrial β-oxidation. A functional peroxisome proliferator-activated receptor (PPAR) responsive element (PPRE) ...
La acidúria 3-hidroxi 3-metilglutàrica: Una malatia molecular per deficiència de 3-hidroxi 3-metilglutaril coenzim A liasa
L'acidúria 3-hidroxi-3-metilglutàrica és una malaltia genètica autosòmica recessiva que es manifesta per una sèrie de símptomes que, en conjunt, s'assemblen a la síndrome de Reye. En aquesta revisió realitzada des de la ...
L'escola i la persona
En aquest debat, doncs, hauríem d'optar per la flexibilitat en la durada de graus i màsters. Per què no podem fer coses diferents en temes diferents? Si ens fixem en els coneixements, és raonable pensar que més durada, més ...
Urgeix el canvi de model universitari
Per tal que el sistema universitari català pugui parlar-se de tu a tu amb altres sistemes moderns és imprescindible que se separi de l'espanyol. No entro aquí en independència política, senzillament un sistema com el del ...
D'ON VINDRAN LES PROTEÏNES?
Els sistemes alimentaris comprenen tots els elements i totes les activitats relacionades amb la producció, processament, distribució, preparació i consum d'aliments, i també els resultats d'aquestes activitats, incloent-hi ...
BioSWR - Semantic Web services Registry for Bioinformatics
Article About the Authors Metrics Comments Related Content Abstract Introduction Functionality Implementation Discussion Acknowledgments Author Contributions References Reader Comments (0) Figures Abstract Despite of the ...
Molecular and functional interaction between GPR18 and cannabinoid CB2 G-protein-coupled receptors. Relevance in neurodegenerative diseases
GPR18, still considered an orphan receptor, may respond to endocannabinoids, whose canonical receptors are CB1 and CB2. GPR18 and CB2 receptors share a role in peripheral immune response regulation and are co-expressed in ...
Mecanismes moleculars associats a la caquèxia cancerosa
La caquèxia és una síndrome complexa que es presenta a més del 65% dels pacients que moren de càncer avançat i, segons Warren (1932), és responsable de la mort del 22% dels pacients afectats per tumors. En aquest sentit, ...
Aquaglyceroporins are differenctially expressed in beige and white adipocytes
Browning of white adipocytes has been proposed as a powerful strategy to overcome metabolic complications, since brown adipocytes are more catabolic, expending energy as a heat form. However, the biological pathways involved ...
The UlaG protein familly defines novel structural and functional motifs grafted on an ancient RNase fold
Background: Bacterial populations are highly successful at colonizing new habitats and adapting to changing environmental conditions, partly due to their capacity to evolve novel virulence and metabolic pathways in response ...
Serum Neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells
Neuregulin 4 (NRG4) has been described to improve metabolic disturbances linked to obesity status in rodent models. The findings in humans are controversial. We aimed to investigate circulating NRG4 in association with ...
Sobre las becas
Hace un mes se presentó en el Ministerio de Ciencia e Innovación el informe Datos y Cifras del Sistema Universitario 2008/2009, documento que anualmente muestra una instantánea de la Universidad española y algunos datos ...
The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive Glut4 glucose transporter
Previously, we have demonstrated that an MEF2 consensus sequence located between −473/−464 in the human GLUT4 gene was essential for both tissue-specific and hormonal/metabolic regulation of GLUT4 expression (Thai, M. V., ...
Reduced adenosine uptake and its contribution to signaling that mediates profibrotic activation in renal tubular epithelial cells: implication in diabetic nephropathy.
Altered nucleoside levels may be linked to pathogenic signaling through adenosine recep- tors. We hypothesized that adenosine dysregulation contributes to fibrosis in diabetic kid- ney disease. Our findings indicate that ...
Neuregulin signaling on glucose transport in muscle cells
Neuregulin-1, a growth factor that potentiates myogenesis induces glucose transport through translocation of glucose transporters, in an additive manner to insulin, in muscle cells. In this study, we examined the signaling ...
